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Iranian Journal of Health Sciences، جلد ۳، شماره ۴، صفحات ۲۴-۳۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The Survival Rate of Childhood Leukemia and Its Related Factors in Kerman, Iran |
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| چکیده انگلیسی مقاله |
Background and Purpose: Leukemia is the most prevalent type of cancer in children and its prognostic factors vary in different geographic locations. The aim of this study was to estimate the 5 years survival rate of children suffering from leukemia in Kerman, Iran and to investigate the factors which might influence it. Materials and Methods: This was a cohort study conducted on patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Cases were all younger than 15 years old admitted to Afzalipour Hospital, Kerman, Iran between 1998 and 2009, and included 219 patients. Survival rates were estimated by applying the Kaplan–Meier method. Log-rank test was used to estimate the statistical difference in survival probability and the effect of independent variables on survival was examined using Cox regression. All analyses were performed using STATA-12. Results: The cumulative 5 years rate of survival in this study was 58% and 43% for ALL and AML, respectively, and the difference was statistically significant (P = 0.0030). Multivariate Cox regression analysis showed that white blood cell (WBC) &ge 50,000 &mul (P = 0.0100) and relapse (P = 0.0060) of ALL patients has a significant effect on survival. In AML due to the small number of patients significant results were not achieved. The cumulative survival rate at the end of 1 year for low, medium and high-risk patients were estimated 97%, 94%, and 78%. Conclusion: Leukemia patients with and WBC &ge 50,000 &mul and a history of relapse had less survival. |
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| کلیدواژه‌های انگلیسی مقاله |
Survival, Cox Regression, Acute Leukemia, Children |
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| نویسندگان مقاله |
مریم پرواره | maryam parvareh
msc student, department of epidemiology and biostatistic, school of health, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)
نرگس خانجانی | narges khanjani
associate professor, department of epidemiology and biostatistic, school of health, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)
زهرا فرهمنی نیا | zahra frahmandinia
assistant professor, department of pediatrics, school of medicine, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)
بیژن نوری | bijan nouri
assistant professor, department of epidemiology and biostatistics, social determinants of health, kurdistan university of medical sciences, sanandaj, iran
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| نشانی اینترنتی |
http://jhs.mazums.ac.ir/browse.php?a_code=A-10-519-2&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
بهداشت |
| نوع مقاله منتشر شده |
پژوهشی |
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