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، جلد ۱۳، شماره ۱، صفحات ۴۱-۴۴
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Histopathological Analysis of Testis: Effects of Astaxanthin Treatment against Nicotine Toxicity |
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| چکیده انگلیسی مقاله |
Background: Nicotine is a toxic compound in the cigarette smoke and has destructive effects on various human organs. Astaxanthin is a carotenoid with high antioxidant property. In this study, we investigated the protective effects of astaxanthin against nicotine-induced toxicity in mice testes. Methods: Forty-two inbred balb/c male mice were divided into six groups:Group 1, received 1 ml normal saline daily; Group 2, received nicotine (1.5mg/kg); Group 3, received astaxanthin (25mg/kg); Group 4, received astaxanthin (50mg/kg); Group 5, received astaxanthin (25mg/kg) plus nicotine (1.5mg/kg); and group 6, received astaxanthin (50mg/kg) plus nicotine (1.5mg/kg). After collecting testes samples, microscopic slides were prepared at the School of Veterinary Medicine, University of Mashhad, and the prepared slides were examined under light microscopy. Results: The histological structures of the testes were normal in the control group and those receiving astaxanthin, regardless of nicotine (groups 3, 4, 5 & 6). However, group 2 that received only nicotine, showed transformed testicular histology with severe hemorrhage. Conclusion: Based on the results, nicotine caused harmful effects on the mice testes and astaxanthin appeared to protect the organs against the toxic effects of nicotine. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
| Bashir Sobhani
PhD student of Veterinary Medicine, Ferdowsi University of Mashhad. Mashhad, Iran.
| Sahar Roomiani
Department of Basic Science, Faculty of Veterinary Medicine, University of Shushtar. Khuzestan, Iran.
| Zahra Ahmadi
Department of Basic Science, Faculty of Veterinary Medicine, University of Shushtar. Khuzestan, Iran.
| Milad Ashrafizadeh
Department of Basic Science, Faculty of Veterinary Medicine, University of Tabriz. Tabriz, Iran.
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| نشانی اینترنتی |
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-540-4&slc_lang=en&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2737/article-2737-2049513.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
پژوهشی |
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