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، جلد ۱۲، شماره ۲، صفحات ۱۵-۲۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
In Vivo Assessment of Gamma Rays, Electron-beam Irradiation plus a Commercial Toxin Binder (Milbond-TX) As an Anti-Aflatoxin B1 in a Chicken Model |
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| چکیده انگلیسی مقاله |
Background: Aspergillus flavus is the most important fungus for production of Aflatoxin B1 (AFB1). This study evaluated the ability of gamma rays (GRs) and electron-beam irradiation (EBI) to counteract the deleterious effects of aflatoxin B1 (AFB1) in a chicken model. Methods: Overall, 168 one-day-old male Coturnix quails were assigned to eight treatments for 42 d in Tehran, Iran, in 2010 and 2011. Two dietary inclusion rates of AFB1 (0 and 2 ppm) and toxin binders, such as 0, 27 kGy doses of GRs, 27 kGy doses of EBI, and 0.3% of commercial toxin binder-milbond-TX, were tested in a 2×4 factorial manner. Serum biochemical parameters, immune response, and dietary treatments on factors associated with kidney and lipid profiles were determined on day 42. Results: AFB1 significantly decreased the hematological parameters (Hematocrit in 21 and 42 d), immune response (White blood cell (WBC), heterophil to lymphocyte ratio (H/L) and sheep red blood cell (SRBC)), and blood chemical factors (glucose, albumin, total protein, and triglycerides) compared to the control diet (P< 0.05). It also significantly increased the calcium, phosphorus, uric acid, and low-density lipoprotein (LDL) levels (P< 0.05). The addition of toxin binders, such as GRs, EBI, and milbond-TX, in the contaminated diets significantly diminished the inhibitory effects of dietary AFB1 (P< 0.05) on the hematological parameters, immune response, blood chemical factors, and factors associated with kidney and lipids profile with no differences compared to the control diet. Conclusion: The addition of these toxin binders may reduce the adverse effects produced by the presence of AFB1 in Japanese quails' diets. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
| Saeed Hasanpour
Department of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran.
| Shaban Rahimi
Department of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran.
| Omid Fani Makki
MSc of Poultry Science, Research and Development Office, Zarin Gostar Sarina Company, Kashmar, Iran.
| Gholamreza Shahhosseini
Department of Agricultural Research, Medicine and Industrial Research School, Karaj, Iran.
| Alireza Khosravi
Department of Mycology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
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| نشانی اینترنتی |
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-65-3&slc_lang=en&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2737/article-2737-2049548.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
عمومی |
| نوع مقاله منتشر شده |
پژوهشی |
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