، جلد ۱۱، شماره ۲، صفحات ۱۵-۱۹

عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله مزوبتوس اپئوس، زهر، عقرب، جذب خوراکی

عنوان انگلیسی Oral Absorption of Mesobuthus eupeus Scorpion Venom in Mice
چکیده انگلیسی مقاله Background: To explore the oral absorption of scorpion venom an ELISA were designed in this study. Scorpions and their venom were been used for centuries as medical treatments in traditional medicine. The oral administration of drug referred as the convenient way, as there was not any publication about gastro-intestinal absorption of scorpion venom; this experiment checked oral absorption of Mesobuthus eupeus scorpion venom in mice. Methods: Six groups of mice orally received 0, 0.2, 0.5, 1, 2 and 5 mg/kg of M. eupeus venom and their blood samples were tacked after 15, 30, 60 min and 2, 4, 6, 24, 48 h after that. The presence of venom the blood samples were detected with a house- antigen capture ELISA. Results: The venom was absorbed after its feeding to mice. The animals expressed no signs of envenomation and, the venom was detectable by AC-ELISA as soon as 15 min after its feed. Maximum serum levels were 2 h after its meal. Conclusion: The orally administrated venom was absorbed to the blood circulation without any clinically symptoms.
کلیدواژه‌های انگلیسی مقاله Mesobuthu Eupeus, Oral Absorption, Scorpion, Venom

نویسندگان مقاله | Zohreh Hosseini
Student of Veterinary Medicine, Shahid Chamran University of Ahvaz, Iran.


| Mohammad Khosravi
Department of Pathobiology, Shahid Chamran University of Ahvaz, Iran.


| Masoud Ghorbanpoor
Department of Pathobiology, Shahid Chamran University of Ahvaz, Iran.


| Mansour Mayahi
Department of Clinical Sciences, Shahid Chamran University of Ahvaz, Iran.



نشانی اینترنتی http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-418-1&slc_lang=en&sid=1
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/2737/article-2737-2049596.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده عمومی
نوع مقاله منتشر شده پژوهشی
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