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، جلد ۶، شماره ۱۸، صفحات ۶۸۱-۶۸۵
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Demographic Information and Clinical and Laboratory Findings in Acetaminophen Poisoning Cases in Rasht, Iran, in 2008 |
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| چکیده انگلیسی مقاله |
Background: Acetaminophen is widely used as an analgesic and antipyretic drug and it is a frequent cause of acute drug poisoning.This study was carried out to investigate the demographic information and clinical and laboratory findings in acetaminophen poisoning patients referred to “17 Shahrivar” and “Razi” educational hospitals, Rasht. Methods: In this retrospective cross-sectional study, 125 patients with acetaminophen poisoning were studied. Descriptive data were analyzed by SPSS software. Results: 90 of the patients were women and the mean age of the patients was 21.5±9.06 years. Also, 72.8% of the patients were from urban areas and most of the patients (67.2%) lived in Rasht. Spring was the most common season for the incidence of poisoning. Suicide was the most common pattern of poisoning (91.2%). The mean time interval between poisoning and use of antidote N-acetylcysteine was 4.94±3.5 hours. The most common cause of delayed administration of antidote was failure in diagnosis of poisoning. Overall, 31.2% of the patients had no significant clinical manifestations. In other patients, nausea (50.4%) was the most common clinical symptom. The most common abnormal laboratory findings were prolonged prothrombin time and international normalized ratio (29%). Liver aminotransferases were elevated only in 18% of the patients. Conclusion: Poisoning with acetaminophen was mainly found in women, 12-20 years of age, in urban areas and spring season. Suicide was the main reason of poisoning. Regarding the most common cause of delay in antidote therapy (failure in poisoning diagnosis), establishment of a toxicology laboratory in Guilan province can help the better management of poisoned patients. |
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| کلیدواژه‌های انگلیسی مقاله |
Acetaminophen, Poisoning, Rasht, Suicide. |
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| نویسندگان مقاله |
علیرضا بادسار | Alireza Badsar
Department of Forensic Medicine and Toxicology, Guilan University of Medical Sciences, Guilan, Iran.
مرتضی رهبر طارمسری | Morteza Rahbar Taramsari
Department of Forensic Medicine and Toxicology, Guilan University of Medical Sciences, Guilan, Iran.
نوذر ستوده فومنی | Nozar Sotodeh Foumani
Student of Medicine ,Guilan University of Medical Sciences, Guilan, Iran.
هانا ابراهیمی | Hannan Ebrahimi
Student of Medicine ,Guilan University of Medical Sciences, Guilan, Iran.
مرتضی فلاح کارکان | Morteza Fallah Karkan
Student of Medicine ,Guilan University of Medical Sciences, Guilan, Iran.
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| نشانی اینترنتی |
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-2-108&slc_lang=en&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2737/article-2737-2049769.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
پژوهشی |
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