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، جلد ۴، شماره ۱، صفحات ۱-۴
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| عنوان انگلیسی |
A Rare Case of Acute Myeloblastc Leukemia With Blast Count Less Than 20% in Bone Marrow |
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| چکیده انگلیسی مقاله |
One of the diagnostic criteria for Acute Myeloblastic Leukemia (AML) is the presence of 20% myeloid blasts in peripheral blood or bone marrow. Some cases with recurrent cytogenetic abnormalities also fall in this category with blast cell count less than 20%. Thus, in the presence of these genetic abnormalities, the patients are classified as AML regardless of blast cell count. One of these genetic heterogeneities is t(8; 21) (q22, q22.1) which is more commonly seen in children and young adults. In this study, a 14-year-old boy is reported with a final diagnosis of AML, which was presented with fever and bicytopenia, clinically suspicious for acute leukemia. Laboratory results reported less than 20% blasts in bone marrow aspiration smears but genetic alteration t(8; 21) (q22, q22.1) was detected by molecular exams. |
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| نویسندگان مقاله |
| Pardis Nematollahi
Department of Hematopathology, Shiraz University of Medical Sciences, Shiraz, Iran. AND MD, Assistant professor, Pathology department, cancer prevention research center, isfahan university of medical science, isfahan, iran
| Behnaz Sabaghi
Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
| Alireza Moafi
Department of Pediatric Hematology and Oncology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
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| نشانی اینترنتی |
http://crcp.tums.ac.ir/index.php/crcp/article/view/210 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2738/article-2738-2049890.pdf |
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