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، جلد ۳، شماره ۴، صفحات ۱۰۶-۱۱۲
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| عنوان فارسی |
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| عنوان انگلیسی |
Anti-Glomerular Basement Membrane Disease With Thrombotic Thrombocytopenic Purpura |
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| چکیده انگلیسی مقاله |
We report a 25-year-old man who was initially presented with Rapidly Progressive Glomerulonephritis (RPGN) in Shahid Modarress Hospital, Tehran, Iran. His diagnosis was Anti-Glomerular Basement Membrane (Anti-GBM) disease that was confirmed by kidney biopsy, as his serum Anti-GBM antibody was undetectable. Although the patient was on cyclophosphamide and high dose prednisolone, he developed Thrombotic Thrombocytopenic Purpura (TTP). We initiated treatment with a high dose of prednisone and plasmapheresis. Because of his poor response, rituximab was administered. After that, the patient’s hematologic criteria and clinical symptoms improved to an acceptable level. Our case is a unique form of negative serum Anti-GBM antibody disease which was complicated with TTP and responded to treatment with rituximab |
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| نویسندگان مقاله |
| Amirhesam Alirezaei
Clinical Research and Development Center, Shahid Modarres Hospital, Shahid Behesht University of Medical Sciences, Tehran, Iran AND Department of Nephrology, School of Medicine Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Mahmood Bakhtiyari
Department of Community Medicine, Faculty of Medicine, Alborz University of Medical Sciences, Karaj, Iran
| Elham Zare
Department of Internal Medicine, School of Medicine, Shahid Behesht University of Medical Sciences, Tehran, Iran.
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| نشانی اینترنتی |
http://crcp.tums.ac.ir/index.php/crcp/article/view/213 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2738/article-2738-2049900.pdf |
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