| چکیده انگلیسی مقاله |
Background: This study aimed to investigate the usage patterns of some parenteral cephalosporins in hospitals affiliated to Shahid Beheshti University of Medical Sciences. The study design consisted of one year before and one year after the implementation of Health Reform Plan (HRP) in Iran.
Methods: The data were collected from 6 university hospitals, including Taleghani, Mofid, Akhtar, Loghman Hakim, Shohadaye Tajrish, and Mahdieh hospitals from 2014 to 2015. The obtained data were analyzed using the GraphPad Prism software. The total consumption of parenteral cephalosporins in the 6 hospitals was expressed in Defined Daily Dose (DDD) per 100 Bed Days (BD).
Results: DDD/100 BD increased from 149.132 to 149.454 DDD/100 one year following the implementation of HRP. This data indicates that the consumption of cefazolin, cefotaxime, ceftizoxime, ceftriaxone, ceftazidime, and cefepime were not significantly changed. Although lower doses (g/d) of ceftizoxime and cefotaxime were used, compared to the standard doses in hospitals, the consumed dose of ceftriaxone (g/d) was significantly higher than the standard DDD.
Conclusion: The obtained results suggest that the HRP was probably not effective in improving irrational antibiotic consumption in Iran. Thus, it is necessary to employ stewardship programs to control such irrational usage. This program should be conducted under the supervision of clinical pharmacists and infectious disease specialists. |
| نویسندگان مقاله |
| Nazila Yousefi
Department of Pharmacoeconomics and Pharma Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Saeide Mirvakili
Department of Pharmacoeconomics and Pharmaceutical Administration, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
| Parisa Akbari
Student Research Committee, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Hesam Sharifnia
Department of Pharmacoeconomics and Pharma Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Ali Saffaei
Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Mehrdad Faizi
Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Farzad Peiravian
Department of Pharmacoeconomics and Pharma Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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