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، جلد ۱، شماره ۳، صفحات ۱-۱۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Dabigatran etexilate - A novel oral anticoagulant for bleeding complications |
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| چکیده انگلیسی مقاله |
Thromboembolic disease is a common cause of morbidity and mortality. Thrombin plays a key role in thrombotic events and thrombin inhibition represents a therapeutic event for thromboembolic events and has been identified as a target of therapy of its pivotal role in coagulation process. Anticoagulation is a major intervention for the management of arterial and venous thromboembolic events. Dabigatran etexilate is an orally effective anti-thrombin drug, several animal and human trials were conformed the efficacy of this drug in reduction of major bleeding in related to acute coronary syndrome, knee replacement surgery and venous thromboembolism conditions. The therapeutic use of this drug also shows limited side effects to select the dabigatran as promising therapeutic agent in bleeding complications. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
| Himabindu Reddy
Department of Pharmacology and Pharmacy Practice, Annamacharya College of Pharmacy, Rajampet, India
| Chakka Gopinath
Department of Pharmacology and Pharmacy Practice, Annamacharya College of Pharmacy, Rajampet, India
| Mohamed Saleem Thattakudian Sheikuduman
Department of Pharmacology and Pharmacy Practice, Annamacharya College of Pharmacy, Rajampet, India
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| نشانی اینترنتی |
http://pbr.mazums.ac.ir/browse.php?a_code=A-10-26-20&slc_lang=en&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2742/article-2742-2202089.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
فارماکولوژی |
| نوع مقاله منتشر شده |
مروری |
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