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، جلد ۱، شماره ۲، صفحات ۲۰-۲۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Evaluation of anti-diabetic effects of hydroalcoholic extract of green tea and cinnamon on streptozotocin-induced diabetic rats |
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| چکیده انگلیسی مقاله |
Today diabetes is one of the most common diseases in the world that affects half of the world population. The use of medicinal herbs especially green tea and cinnamon has been taken into consideration for relieving the symptoms of diabetes, but there were some different ideas about their effectiveness. So, this study was conducted to evaluate the effect of cinnamon and green tea extract, individually and in combination, on blood glucose and weight loss in diabetic mice with Streptozotocin (STZ). The experiment was performed on 50 Wistar rats. A total of 50 rats were divided into 10 groups of 5 and STZ was injected at the dose of 40 mg/kg/day for 5 days intraperitoneally. After diabetes induction, three groups received, 50, 100 and 200 mg doses of green tea extract, three groups received 50, 100 and 200 mg doses of cinnamon extract and three final groups received 50, 100 and 200 mg doses of cinnamon and green tea in combination by gavages daily for 6 weeks. After each period of treatments, blood glucose and the weight of animals were determined. At the end of the sixth week, blood glucose and weight loss were improved in diabetic rats in a dose-dependent manner and the dose of 200 mg/kg extract cinnamon with green tea had the most appropriate synergic effect. |
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| کلیدواژه‌های انگلیسی مقاله |
Cinnamon, green tea, diabetes, streptozotocin |
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| نویسندگان مقاله |
| Ghasem Shokri
Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran
| Hamed Fathi
Department of Biology, Payame Noor University, Tehran,Iran
| Majid Jafari Sabet
Department of Pharmacology, Iran University of Medical Sciences, Tehran, Iran
| Nafiseh Nasri Nasrabadi
Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran
| Ramin Ataee
Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran
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| نشانی اینترنتی |
http://pbr.mazums.ac.ir/browse.php?a_code=A-10-26-12&slc_lang=en&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2742/article-2742-2202098.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
ترکیبات طبیعی |
| نوع مقاله منتشر شده |
پژوهشی |
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