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Anatomical Sciences Journal، جلد ۷، شماره ۲۷، صفحات ۰-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Effects of Different Doses of Lif on Ivm Rate and Cumulus Expansion In Mouse Oocytes |
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| چکیده انگلیسی مقاله |
Purpose: The aim of this research was to study the effects of different doses of LIF on GVBD and MII development rate and cumulus expansion. Materials and Methods: Immature mice superovulated with HMG and GV oocytes obtained from ovary 48 hours later. The GV oocytes were cultured in TCM199 with 100, 500 and 1000 IU /ml LIF. Cumulus expansions were evaluated with two examiners and numbers of MII oocytes were recorded. For denuding the oocytes hyaloronidase was used.Results: Our results showed that the rate of GVBD and MII development increased in groups with LIF compared with control group. Rate of MII development with 1000 IU/ml LIF was significantly higherthan that of control group (P< 0.05). Cumulus expansion in group with 1000 IU/ml LIF improved significantly compared with control group (p< 0.05). Conclusion: Our results showed that LIF could improve IVM rate in dose dependant. Also cumulus expansion improved in group with LIF and increased oocyte quality. |
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| کلیدواژه‌های انگلیسی مقاله |
Lif, Ivm, Ivf, Cumulus Expansion, Mouse |
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| نویسندگان مقاله |
| Ameneh Mohammadi Roushandeh
| Hassan Haji Hosseinlou
| Behrouz Niknafs
| Raheleh Halabian
| Mahdi Rouhbakhsh
| Monireh Daneshvar
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| نشانی اینترنتی |
http://anatomyjournal.ir/browse.php?a_code=A-10-304-181&slc_lang=fa&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
Morphometry |
| نوع مقاله منتشر شده |
Original |
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