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Caspian Journal of Neurological Sciences، جلد ۷، شماره ۳، صفحات ۱۳۳-۱۳۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The Relationship Between Serum Dehydroepiandrosterone Concentration and Memory Function in the Elderly |
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| چکیده انگلیسی مقاله |
Background: World population is rapidly aging, and the elderly are most at risk of cognitive impairment. Dehydroepiandrosterone (DHEA) and DHEA-Sulfate (DHEAS) have an essential effect on neuroprotection and might effectively improve cognition and memory. Objectives: This study aimed to investigate the relationship between the level of DHEA and memory function in the elderly. Materials & Methods: The present study was a cross-sectional analytical study, and the study population included the elderly (age 60 years and older) living in Rasht City, the north of Iran, in 2020. The participants completed a demographic questionnaire and Wechsler Memory Scale (WMS), and their serum DHEA levels were measured by the hormonal automation method. The data were analyzed by SPSS v. 23, using t-test, the one-way Analysis of Variance (ANOVA), Pearson and Spearman correlation coefficient. Results: The participants included 100 older people (57 females and 43 males) with a Mean±SD age of 67.38±5.39 years. There was no correlation between serum DHEA concentrations with a total score of the WMS (r=0.117, P=0.247). However, the correlation between the DHEA level and the scores of personal and current information and visual reproduction subscales were statistically significant (r=0.219, P=0.029; r=0.206, P=0.04). Conclusion: The study indicates that the total memory score was not associated with the level of serum DHEA. |
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| کلیدواژه‌های انگلیسی مقاله |
Dehydroepiandrosterone, Memory, Wechsler Memory Scale |
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| نویسندگان مقاله |
| Elahe Abdollahi
Kavosh Cognitive Behavior Sciences and Addiction Research Center, Department of Psychiatry, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
| Golsa Olia
Kavosh Cognitive Behavior Sciences and Addiction Research Center, Department of Psychiatry, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
| Fatemeh Eslamdoust-Siahestalkhi
Kavosh Cognitive Behavior Sciences and Addiction Research Center, Department of Psychiatry, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
| Robabeh Soleimani
Kavosh Cognitive Behavior Sciences and Addiction Research Center, Department of Psychiatry, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
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| نشانی اینترنتی |
http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-135&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
پژوهشی |
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