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، جلد ۸، شماره ۳، صفحات ۱۲۵-۱۳۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Anticoagulative Effect of Two Species of Brown Algae; Sargassum Angustifolium and Cystoseira Indica |
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| چکیده انگلیسی مقاله |
Background: Fucoidans are a group of sulfated fucose-rich polysaccharides that are isolated from brown marine algae and echinoderms, and recently have been found in seagrasses. Fucoidans, as well as their derivatives, have several beneficial biological effects and therapeutic potentials. In the present study, we aimed to evaluate the anticoagulative effects of two species of brown algae, namely Sargassum angustifolium (S. angustifolium) and Cystoseira indica (C. indica). Methods: Fucoidan C and fucoidan S were extracted by an ethanol/water solvent system from S. angustifolium and C. indicia, respectively. The anticoagulative effects of fucoidan C and fucoidan S were tested on 10 normal serum samples by evaluating the rate of thrombin time (PT) and prothrombin time (PTT). Results: Both fucoidan C and fucoidan S significantly increased PTT. However, no significant difference was observed in PT. Fucoidan C had a greater effect on PTT prolongation compared with fucoidan S. Conclusion: Both fucoidans extracted from S. angustifolium and C. indicia can be used as anticoagulants in biotechnology and human disorders. |
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| کلیدواژه‌های انگلیسی مقاله |
Fucoidan, Sargassum angustifolium, Cystoseira indica, Anticoagulation |
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| نویسندگان مقاله |
| Narges Obeidi
Department of Hematology, School of Para Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.
| Mohammad Javad Mousavi
Department of Hematology, School of Para Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.
| Arghavan Hosseinpouri
Department of Cellular and Molecular Sciences, Faculty of Sciences, Persian Gulf University, Bushehr, Iran.
| Hamideh Malekhayati
Student Research Committee, Bushehr University of Medical Sciences, Bushehr, Iran.
| Elham Ehsandoost
Department of Food Science & Technology, Shiraz University, Shiraz, Iran.
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| نشانی اینترنتی |
http://rmm.mazums.ac.ir/browse.php?a_code=A-10-1099-3&slc_lang=en&sid=1 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
هماتولوژی و آنکولوژی |
| نوع مقاله منتشر شده |
پژوهشی |
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