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، جلد ۷، شماره ۱، صفحات ۹-۱۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Two Successful Bone Functions in Patients with Chronic Granulomatous Disease Marrow Transplantations Improved Lung |
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| چکیده انگلیسی مقاله |
Chronic Granulomatous Disease (CGD) is a rare inherited primary immune deficiency disorder with defective respiratory burst activity in phagocytes, resulting in recurrent pyogenic infections. In this study, we described two CGD patients who had done bone marrow transplantation (BMT). As Bone marrow transplantation (BMT) is the definitive treatment of the disease, we evaluated the function of their lungs before and after BMT. In both patients, the BMT was from their siblings. In case 1, the patient’s pulmonary function (PFT) before BMT was: FEV1: 34, FVC: 40, FEV1 / FVC: 72%, and after BMT was: FEV1: 66, FVC: 40 by 49, FEV1 / FVC: 64%. In case 2, the patient’s PFT before BMT was: FEV1: 22, FVC: 36, FEV1 / FVC: 41%, and after BMT was: FEV1: 47, FVC: 33, FEV1/FVC: 43%. BMT significantly improved their Pulmonary Problems and Preclinical (PFT). In addition, after BMT, both patients’ well-tolerated clinical signs and the infection rate, and the number of hospitalizations in both patients decreased. |
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| کلیدواژههای انگلیسی مقاله |
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| نویسندگان مقاله |
| Mahsa Rekabi
Pediatric Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung, Tehran, Iran.
| Farhad Seif
Department of Immunology and Allergy, Academic Center for Education, Culture, and Research, Tehran, Iran.AND Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran.
| Farzad Nouri
Pediatric Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung, Tehran, Iran.
| Alireza Mahdaviani
Pediatric Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung, Tehran, Iran.
| Ali Akbar Velayati
velayati @ theaasm . org
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| نشانی اینترنتی |
https://crcp.tums.ac.ir/index.php/crcp/article/view/488 |
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