، جلد ۶، شماره ۴، صفحات ۱۴۵-۱۴۹

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عنوان انگلیسی Acute Hemolytic Anemia Induced by Levofloxacin in a Woman With G6PD Deficiency: A Case Report
چکیده انگلیسی مقاله Introduction: Glucose 6-Phosphate Dehydrogenase deficiency (G6PD) is an X-linked recessive disorder recognized as the most prevalent enzyme deficiency around the world. G6PD deficiency has a high prevalence in Iran, especially in the northern regions. As we know, hemolysis in G6PD patients was not reported with levofloxacin previously.  Case Report: In this report, we introduce a 54-year-old G6PD deficient woman who experienced the symptoms of hemolytic anemia following completion of treatment with levofloxacin. Result: After ruling out other causes of hemolysis, by using the Naranjo scale, levofloxacin was considered as a possible cause of hemolysis. Conclusion: Though the hemolytic anemia induced by levofloxacin is extremely rare in G6PD deficient patients, drug-induced hemolytic anemia should be considered as one of the differential diagnoses. It would be appropriate to use an alternative antibiotic instead of levofloxacin in a G6PD deficient patient.  
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نویسندگان مقاله | Ebrahim Salehifar
Department of Clinical Pharmacy, Pharmaceutical Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.


| Masoud Aliyali
Associate Professor of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran


| aliyeh bazi
Department of Clinical Pharmacy, Pharmaceutical Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.



نشانی اینترنتی https://crcp.tums.ac.ir/index.php/crcp/article/view/402
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