، جلد ۵، شماره ۳، صفحات ۸۶-۸۸

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عنوان انگلیسی Carbamazepine and Hyperpigmentation in a Young Woman: A Case Report
چکیده انگلیسی مقاله Carbamazepine(CBZ) is an effective first line treatment for trigeminal neuralgia and has an important place in the management of epilepsy and bipolar disorder. The potential for clinically important drug interactions exists because CBZ may induce the hepatic metabolism of other drugs or, conversely, other drugs may induce or inhibit the metabolism of CBZ.CBZ  is including  big group   of antiepileptic drugs that is widely used to prevent and control seizures. It has been associated with several cutaneous side effects, in  this case reported  a young woman who presented  with dyspnea, weight loss, pancytopenia, abdominal pain and oligomenorrhea and two weeks history of hyperpigmented lesions over her face, neck and two hands. She had history of seizures and did well on carbamazepine for 7 months ago, carbamazepine was withdrawn and she was treated with local emollients. The lesions were partially improved in 2 weeks.
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نویسندگان مقاله | Mona Talaschian
Department of Internal Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.


| Anahita Sadeghi
Digestive Diseases Research Institute, Shariati Hospital ,Tehran University of Medical Sciences, Tehran, Iran.


| Sara Pakzad
Department of Medical-Surgical Nursing, School Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran.



نشانی اینترنتی https://crcp.tums.ac.ir/index.php/crcp/article/view/341
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