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، جلد ۷، شماره ۲، صفحات ۱۰۵-۱۱۴
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Evaluation of Susceptibility and Resistance of Human Infectious Bacteria and Identification of Bioactive Compounds in Pistacia atlantica, Cassia absus, and Quercus persica |
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| چکیده انگلیسی مقاله |
Background: The antimicrobial activity of plants has long been considered an effective mechanism for controlling pathogenic microorganisms. Objectives: This study aimed to identify phytochemical compounds of the seed extracts from ethnomedicinal plants of Pistacia atlantica, Cassia absus, and Quercus persica with Gas Chromatography-Mass Spectrometry (GC-MS) and investigation of their antibacterial and antioxidant activities. Methods: The seeds were collected from Lorestan Province, Iran. Their antibacterial and anti-radical activities were analyzed by disk-diffusion and 2,2-diphenyl-1-picrylhydrazyl assays, respectively. Ethanol (96%), methanol (80%), and distilled water extracts were obtained by the maceration method. The methanol extract was used for the analysis of chemical compositions. Results: About 40, 31, and 8 compounds were identified by GC-MS in the seeds of C. absus, P. atlantica, and Q. persica, respectively. Results indicated that 2,4-di-tert-butylphenol (36.043%) and tetradecanoic acid (4.92%) were dominated in the seed extracts of C. absus. However, germacyclopetene (38.119%) and 1,2,3-benzenetriol (8.115%) were dominated in the seed extracts of P. atlantica. Furthermore, 5H-tetrazole-5-thione, 1,4-dihydro-1,4-dimethy (38.505%), and tetradecanoic acid (30.546%) were dominated in the seed extracts of Q. persica. The highest inhibitory activity against Micrococcus luteus was observed on the methanol extract of C. absus with ascorbic acid. A significant difference was observed between the Inhibitory Concentration (IC50) values of methanol extract of C. absus with ascorbic acid. Conclusion: Because of the presence of antimicrobial compounds in the tested ethnomedicinal plants, they can be used to synthesize new antimicrobial drugs in medicinal and pharmaceutical sciences. |
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| کلیدواژه‌های انگلیسی مقاله |
Gas Chromatography-Mass Spectrometry (GC/MS), Cassia absus, Pistacia atlantica, Quercus persica, Infectious bacteria |
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| نویسندگان مقاله |
| Mostafa Alamholo
Department of Biotechnology, Institute of Science and Modern Technology, Rojava University, Qamishlo, Syria.
| Yosof Amraie
Department of Plant Biotechnology, Faculty of Agriculture, Bu-Ali Sina University, Hamadan, Iran.
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| نشانی اینترنتی |
http://pbr.mazums.ac.ir/browse.php?a_code=A-10-800-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
شیمی دارویی |
| نوع مقاله منتشر شده |
پژوهشی |
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