Journal of Pediatrics Review، جلد ۱۰، شماره ۴، صفحات ۲۷۷-۲۸۶

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عنوان انگلیسی COVID-19 in Children With Inflammatory Bowel Disease: A Systematic Review
چکیده انگلیسی مقاله Background: Considering the chronic immunosuppression in Inflammatory Bowel Disease (IBD) patients, it is necessary to evaluate the course of COVID-19 in these patients. Studies have shown various results in adult IBD patients. This study aimed to find out the course of this infection in pediatric IBD patients.  Methods: This was a systematic review study according to the PRISMA 2020 guideline. International databases including Scopus, PubMed, and the Web of Science were searched with a combination of "COVID-19" AND "IBD" or synonyms until October 16, 2021. Studies that have reported the outcomes of COVID-19 infection in patients less than 19 years of age were selected. Name of author, country, study duration and type, IBD type and drugs, and COVID-19 outcomes were extracted. Results: From the initially retrieved 2215 articles, finally 16 articles were eligible. Data from 1040 pediatric IBD patients were reported. Twenty-four patients were hospitalized, 5 developed patients multisystem inflammatory syndrome in children, and others had a mild disease course and were outpatient. Steroid use, severe IBD activity, and comorbidities were shown to increase risk of hospitalization and disease severity. Conclusions: COVID-19 is a benign and self-limited disease in pediatric IBD patients. Comorbidities, steroid use, and severe IBD activity affect the outcomes.
کلیدواژه‌های انگلیسی مقاله Coronavirus disease 2019, Inflammatory bowel disease, SARS-CoV-2, Pediatrics

نویسندگان مقاله | Peiman Nasri
Metabolic Liver Disease Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.


| Somayeh Sadeghi
Acquired Immunodeficiency Research Center, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.


| Silva Hovsepian
Metabolic Liver Disease Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.


| Rojin Chegini
Metabolic Liver Disease Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.


| Shahrzad Soltani Esmaeili
Department of Pediatrics, School of Medicine, Imam Hossein Children’s Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.


| Gelareh Kiani
Department of Pediatrics, School of Medicine, Imam Hossein Children’s Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.



نشانی اینترنتی http://jpr.mazums.ac.ir/browse.php?a_code=A-10-1059-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Pediatric Gastroenterology
نوع مقاله منتشر شده Systematic Review
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