Basic and Clinical Neuroscience، جلد ۱۳، شماره ۶، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Impact of Transcranial Direct Current Stimulation (tDCS) on Ultra Rapid Opioid Detoxification (UROD) Outcome
چکیده انگلیسی مقاله Background: Persistence of post-detoxification problems in drug addiction is one of the disadvantages of the ultra-rapid opioid detoxification (UROD) method. Transcranial direct current stimulation (tDCS) has been introduced in experimental addiction treatment for some years. Results of pilot studies suggest that it might be a promising method for addiction treatment. Objectives: This study explores the adjunctive application of Transcranial direct current stimulation during treatment of opiate addiction with the ultra-rapid opioid detoxification approach. Methods: This double blind sham-controlled clinical trial was carried out on patients with substance abuse admitted to the Bahman clinic of Yazd in Iran (March to September- 2014). Forty participants were randomly allocated to treatment and control groups. Two sessions of transcranial direct current stimulation (real or sham) over dorsolateral prefrontal cortices (DLPFC) were applied accompanied by ultra-rapid opioid detoxification. Withdrawal symptoms and craving were assessed by the Drug Desire Questionnaire (DDQ) and Objective Opiate withdrawal scale (OOWS) prior to ultra-rapid opioid detoxification as well as for the 24- hour interval after ultra-rapid opioid detoxification. Results: Transcranial direct current stimulation optimized the opiate addiction treatment through craving and the withdrawal syndrome alleviation and. Conclusions: The results of the study indicate that prefrontal transcranial direct current stimulation may promote the efficacy of the ultra-rapid opioid detoxification method in opioid addiction.
کلیدواژه‌های انگلیسی مقاله Craving, Transcranial direct current stimulation, Substance withdrawal syndrome , Opioid-related disorders
نویسندگان مقاله | Hamid Mirhosseini
Department of Psychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| Masoud Kargar
Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| Michael Nitsche
Department of Neurology, University Medical Hospital Bergmannsheil, Bochum, Germany. Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany.


| Mohammad Ali Sheikhi Abarghouei
Department of Anesthesia and Intensive Care, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| Mohammad Ali Nazari
Department of Psychology, Neuroscience laboratory, University of Tabriz, Tabriz, Iran.


| Ghasem Dastjerdi
Department of Psychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
نشانی اینترنتی http://bcn.iums.ac.ir/browse.php?a_code=A-10-1573-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Cellular and molecular Neuroscience
نوع مقاله منتشر شده Original
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