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Caspian Journal of Neurological Sciences، جلد ۲، شماره ۴، صفحات ۲۹-۳۵
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Helicobacter pylori and Migraine: Is Eradication of Helicobacter pylori Effective in Relief of Migraine Headache? |
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| چکیده انگلیسی مقاله |
Background: Association between Helicobacter pylori (HP) infection and migraine and the effect of HP eradication on relief of migraine headache have been studied but the results are controversial. Objectives: To evaluate the effect of HP eradication in treatment of patients affected by migraine. Materials and Methods: Eighty consecutive HP infected patients affected by migraine without aura were enrolled in this clinical trial. They have referred to an endoscopy clinic for work-up of HP infection from October 2013 to November 2014. Patients were randomly assigned in 2 groups using 2 different regimens; Group A: migraine treatment and a 14-day triple therapy for HP infection and Group B: migraine treatment without HP eradication. The mean duration (hour), headache severity (MIDAS) and the frequency (per month) of clinical headache attacks were calculated upon enrollment in the study and at 6 months and 12 months after treatment. All data were analyzed using SPSS version 16. Comparison of categorical variables across the groups was performed using Chi-square test. Results: In group A, HP infection was eradicated in 34 of 40 patients (85%). After treatment in eradicated patients compared with the control group there was significant decrease in severity and frequency (but not in duration) of the migraine attacks at 6 months (p< 0.001) and significant decrease in intensity, frequency and duration of the migraine attacks at 12 months (p< 0.001). Conclusion: HP should be considered and examined in migranous patients and eradication treatment can be beneficial for relief of clinical attacks. |
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| کلیدواژه‌های انگلیسی مقاله |
Helicobacter pylori, Disease Eradication, Migraine Disorders |
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| نویسندگان مقاله |
محمدرضا سید مجیدی | mohammadreza seyyedmajidi
سید امیر banikarim | seyed amir banikarim
افسانه اردلان | afsaneh ardalan
سید حسین هژبرالساداتی | seyed hossein hozhabrossadati
علیرضا نوروزی | alireza norouzi
جمشید وفایی منش | jamshid vafaeimanesh
gastroenterology and hepatology research center, qom university of medical sciences, qom, iran ; j.vafaeemanesh@muq.ac.ir
سازمان اصلی تایید شده: دانشگاه علوم پزشکی قم (Qom university of medical sciences)
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| نشانی اینترنتی |
http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-29&slc_lang=en&sid=en |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/1782/article-1782-282248.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
پژوهشی |
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