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Caspian Journal of Neurological Sciences، جلد ۲، شماره ۴، صفحات ۴۲-۵۳
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Grading of Glioma Tumors by Analysis of Minimum Apparent Diffusion Coefficient and Maximum Relative Cerebral Blood Volume |
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| چکیده انگلیسی مقاله |
Background: Gliomas are the most common primary neoplasms of the central nervous system. Relative cerebral blood volume (rCBV) could estimate high-grade Gliomas computed with dynamic susceptibility contrast MR imaging which it is artificially lowered by contrast extravasation through a disrupted blood-brain barrier. Objectives: Our intent was to clarify the usefulness of diffusion-weighted magnetic resonance imaging (DWI) and perfusion weighted magnetic resonance imaging (PWI) in the grading of Gliomas. Materials and Methods: Both PWI and DWI with a three-tesla scanner investigated nineteen consecutive patients with Gliomas. The means of rCBV and ADC values have been compared among the tumor groups with t-test and ROC curve analysis to determine threshold values of Gliomas grading. Results: Mean maximum rCBV were 2.71±1.41 for low grades (I & II), and 8.14±2.58 for high grades (III & IV) Gliomas (p=0.001). Mean minimum ADC were 1.47±.46 ×103 mm2/s for low grades (I & II), and .47±.38×103 mm2/s for high grades (III & IV) Gliomas (p=0.001). We can get 0.94×103 mm2/s for minimum ADC and 3.85 for maximum rCBV as a difference cutoff point between low and high-grade Gliomas. Conclusion: Combination of both DWI and PWI techniques, with measurement of minimum ADC and maximum rCBV can be used to distinguish between high grade and low-grade Glioma tumors. |
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| کلیدواژه‌های انگلیسی مقاله |
Diffusion Magnetic Resonance Imaging, Neoplasm Grading |
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| نویسندگان مقاله |
مهدیه صابری | mahdiyeh saberi
فریبرز فایقی | fariborz faeghi
medical physicist, assistant professor of medical imaging, department of radiology technology, faculty of allied medical sciences, shahid beheshti university of medical sciences, tehran, iran ; f_faeghi@sbmu.ac.ir
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)
حسین قناعتی | hossein ghanaati
مجتبی میری | mojtaba miri
ایوب رستم زاده | ayoob rostamzadeh
سهیلا خداکریم | soheila khodakarim
فرهاد نعلینی | farhad naleini
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| نشانی اینترنتی |
http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-31&slc_lang=en&sid=en |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/1782/article-1782-282250.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
پژوهشی |
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