Caspian Journal of Neurological Sciences، جلد ۱، شماره ۳، صفحات ۳۳-۴۰

عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله

عنوان انگلیسی Determination the Proportion of Refractory Epilepsy and Some Associated Factors in Epileptic Patients in the North East of Iran
چکیده انگلیسی مقاله Background: Epilepsy is the second common neurologic disorder. Although many antiepileptic drugs have been formulated to control the seizures, but not all seizures have been controlled by them. Uncontrolled epilepsy can actually reduce the patients’ quality of life. Objectives: Identifying the proportion of adult intractable epilepsy among epileptic patients in an area in the North East of Iran Materials and Methods: All epileptic patients who admitted to neurology clinic of a teaching hospital associated with Islamic Azad University of Mashhad in 2014 that were eligible for inclusion criteria enrolled this cross-sectional study. After fulfilling the informed consent, interview, examination and EEG were done. The data was expressed and analyzed by using Mean±Standard deviation and the Likelihood Ratio Chi-Square test in SPSS software version 22. Significance level was considered as less than 0.05%. Results: From 171 patients, 59 patients with epilepsy (34.5%) met the criteria for intractable epilepsy (37.5% male, 31.3% female) with mean age of 28.2±8.5 years. The mean duration of disease was 14.5±8.4 and 11±8.8 years in patients with refractory epilepsy and controlled epilepsy respectively (t-test=2.5 and p=0.013). The seizure frequency was significantly higher in pharmacoresistant patients than pharmacoresponsive ones (7.15±8.4 vs. 0.29±7 per month p=0.0001). Also taking Carbamazepin and Clobazam and Primidone were associated with intractable epilepsy (p< 0.05). Conclusions: Our results accounted that about one-third of patients with epilepsy are categorized in refractory epilepsy with higher duration of disease.
کلیدواژه‌های انگلیسی مقاله Epilepsy, Prevalence

نویسندگان مقاله مهران همام | mehran homam


آرزو فرج پور | arezou farajpour


محسن آقایی حکاک | mohsen aghaee hakak


حمیدرضا حاتمیان | hamidreza hatamian


آتوسا خلیل پور تیلمی | atousa khalil pour
mashhad branch, islamic azad university, mashhad, iran ; htasbamtassa@yahoo.com

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)


نشانی اینترنتی http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-23&slc_lang=en&sid=en
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/1782/article-1782-282256.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده تخصصی
نوع مقاله منتشر شده پژوهشی
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