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Pharmaceutical and Biomedical Research، جلد ۱، شماره ۱، صفحات ۳۷-۴۳
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Antioxidant properties of Helichrysum pseudoplicatum Nab |
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| چکیده انگلیسی مقاله |
The genus Helichrysum (Asteraceae),is comprised of approximately 500-600 species and used for the treatment of a variety of pathological conditions in folk medicine in many countries. In this study, antioxidant activities of aerial parts ofH. pseudoplicatum were investigated employing various in vitro assay systems, i.e. 2,2-diphenyl-1-picrylhydrazyl (DPPH) and nitric oxide radical scavenging, reducing power and hydrogen peroxide scavenging. IC50 for DPPH radical-scavenging activity was 438.9 ± 15.6 µg ml-1. The extract exhibited good reducing power at 25 - 400 µg ml-1 but was not comparable with that of vitamin C. The extract showed good nitric oxide-scavenging activity. IC50 was 474.3 ± 11.8 µg ml-1.It was capable of scavenging hydrogen peroxide in a concentration dependent manner. It showed good activity. Its IC50 was 159.8 ± 8.2 µg ml-1.The IC50 values for ascorbic acid and BHA were 21.4 and 52.0 µg ml-1, respectively. The total amount of phenolic compounds in the extract was determined as gallic acid equivalents (22.7 ± 3.1 mg /g of extract) and total flavonoid contents were calculated as quercetin equivalents (9.6 ± 1.3 mg /g of extract) from a calibration curve. This plant contained low amount of total flavonoids and phenolic compounds. Its moderate antioxidant activities may be attributed to its low levels of phenols and flavonoids. |
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| نویسندگان مقاله |
محمد علی ابراهیم زاده | mohammad ali ebrahimzadeh
pharmaceutical sciences research center, school of pharmacy, mazandaran university of medical sciences, sari, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)
افسانه توسلی | afsaneh tavassoli
research center of natural resources of mazandaran, sari, iran.
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| نشانی اینترنتی |
http://pbr.mazums.ac.ir/browse.php?a_code=A-10-26-5&slc_lang=en&sid=en |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/1789/article-1789-282470.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
ترکیبات طبیعی |
| نوع مقاله منتشر شده |
پژوهشی |
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