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Basic and Clinical Neuroscience، جلد ۱۴، شماره ۶، صفحات ۰-۰
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عنوان فارسی |
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چکیده فارسی مقاله |
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کلیدواژههای فارسی مقاله |
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عنوان انگلیسی |
Adverse Drug Reactions of Multiple Sclerosis Disease-Modifying Drugs |
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چکیده انگلیسی مقاله |
Introduction: High frequency of adverse drug reactions (ADRs) challenges multiple sclerosis (MS) treatment. We aimed to assess the nature and frequency of ADRs induced by MS medications in an observational cross-sectional study. Material and Methods: ADRs of all outpatients who had been visiting a neurologist and had been receiving at least one disease-modifying therapy (DMT) for MS during the last three months were investigated. Results: A total number of 484 ADRs were detected in these patients. The preventability rate was 5.9%, and 0.61% of reactions were serious. Discussion: The high frequency of adverse drug reactions in this study shows a strong need for planning a strategy to increase patients' adherence to treatment. |
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کلیدواژههای انگلیسی مقاله |
Adverse drug reactions, Interferons, Neuropharmacology, Neurology, Compliance |
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نویسندگان مقاله |
| Maryam Salehbayat International Campus, Tehran University of Medical Sciences, Tehran, Iran.
| Roya Abolfazli Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran.
| Niayesh Mohebbi Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences,Tehran, Iran.
| Seyed Mehrdad Savar Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran.
| Gloria Shalviri Tehran University of Medical Sciences, Tehran, Iran.
| Kheirollah Gholami Pharmacoepidemiology and Pharmacovigilance Center, Food and Drug Administration, Ministry of Health, Tehran, Iran.
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نشانی اینترنتی |
http://bcn.iums.ac.ir/browse.php?a_code=A-10-2848-2&slc_lang=en&sid=1 |
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زبان مقاله منتشر شده |
en |
موضوعات مقاله منتشر شده |
Clinical Neuroscience |
نوع مقاله منتشر شده |
Commentary |
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