|
|
Journal of Pediatrics Review، جلد ۱۲، شماره ۱، صفحات ۰-۰
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژههای فارسی مقاله |
|
|
| عنوان انگلیسی |
Beta Thalassemia Patients and Their Growth, a Mini Review and Our Clinical Experience |
|
| چکیده انگلیسی مقاله |
Background: The prevalence of short stature was reported high in thalassemia major patients. It causes mental and social problems for them. As different cut-off points for growth retardation are suggested in these patients, it is desirable to find a careful cut-off age using statistical analysis to help patients before it is too late.
Evidence Acquisition: Data from 803 thalassemia major patients was extracted from questionnaires completed in person by the operator. They contained demographic data, family, medical, and drug history. Height and weight measurements were conducted by only one device. The mean age was 20 ± 7 years and there were 420 females in the sample. Children (less than 20 years of age) constituted 47% of the participants. Patients who reported a major risk factor for osteoporosis were omitted from this study. The SPSS software was used for the statistical analysis
Results: Short stature was found in 32% of patients. Being 10 to 11 years old or above increased the risk of short stature, 28.5 and 21.4 times, respectively compared to younger patients (P values < 0.001). On the other hand, after 7 years of age up to 18 years of age, similar to 10 years of age and 11 years of age, increases the risk of short stature. Also being 27 years old and 30 years old and above increases the risk of short stature 1.4 and 1.7 times, respectively, compared to younger patients (P values = 0.042 and < 0.018, respectively).
Conclusions: Awareness of short stature and monitoring it in thalassemic patients should be done in their childhood. Accordingly, being 7 years old or above increases the risk of short stature; therefore, we suggest the start of monitoring as early as 5 years of age. |
|
| کلیدواژههای انگلیسی مقاله |
Cut-off point, Growth, Thalassemia, Bone mineral density, Short stature |
|
| نویسندگان مقاله |
| Mohammad-Reza Mohajeri-Tehrani
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
| Faezeh Arab
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
| Sedigheh Salemkar
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
| Najmeh Darvishian
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
| Fariba Mohseni
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
| Bagher Larijani
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
| Zohreh Hamidi
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
|
|
| نشانی اینترنتی |
http://jpr.mazums.ac.ir/browse.php?a_code=A-10-1081-1&slc_lang=en&sid=1 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Endocrinology |
| نوع مقاله منتشر شده |
Research Article |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|