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Basic and Clinical Neuroscience، جلد ۱۵، شماره ۲، صفحات ۱۸۵-۱۹۸
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Environmental Effect of High-voltage Towers on the Cerebellum and Cognitive Impairments in the Monkey |
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| چکیده انگلیسی مقاله |
Introduction: Today, high-voltage (HV) lines create a pernicious environment for humans living or working in the vicinity and even under these lines. The male rhesus monkey is used to investigate the effects of fields produced by HV towers. This study examines the function and level of impact in rhesus monkeys’ brains from the cerebellum’s cognitive, biological, and structural perspective.
Methods: Two monkeys have been used, one as a control and the second as a test. The monkey under test was subjected to a simulated HV electrical field of 3 kV/m, 4 hours a day, for 1 month. Behavioral tests were performed using a device designed and built for this purpose. Concentration analysis of adrenocorticotropic hormones (ACTH) and inspection of glucocorticoid receptor gene’s (GR) expression were performed by the reverse transcription polymerase chain reaction method. Changes in cerebellar anatomy were examined with magnetic resonance imaging (MRI). All tests were performed before and after the study period and compared with the control monkey.
Results: Cognitive tests showed a significant reduction for the monkey exposed to the HV electrical field in the first week after imposition compared with the same time before. Also, the expression of the GR gene decreased, and the concentration of ACTH hormone in plasma increased. Surveying the level of cerebral MRI images did not show any difference, but hemorrhage was evident in a part of the cerebellum.
Conclusion: The tested monkey’s cognitive, biological, and MRI results showed a decrease in visual learning and memory indices. |
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| کلیدواژه‌های انگلیسی مقاله |
Cerebellum, Memory, Monkey, Learning, Rhesus, Elecromagnetic fields |
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| نویسندگان مقاله |
| Hamed Aliyari
Department of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, United States.
| Hedayat Sahraei
Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
| Mohammad Bagher Menhaj
Department of Electrical Engineering, School of Electrical, Computer & Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran.
| Masoomeh Kazemi
Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
| Behrooz Vahidi
Department of Electrical Engineering, School of Electrical, Computer & Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran.
| Seyed Hossein Hosseinian
Department of Electrical Engineering, School of Electrical, Computer & Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran.
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| نشانی اینترنتی |
http://bcn.iums.ac.ir/browse.php?a_code=A-10-1340-5&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Cognitive Neuroscience |
| نوع مقاله منتشر شده |
Original |
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