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، جلد ۴، شماره ۲، صفحات ۵۹-۶۶
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Investigating the MRI Lesions and Their Relationship With Cognition Condition for Multiple Sclerosis |
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| چکیده انگلیسی مقاله |
Background and Aim: Multiple sclerosis (MS) is a common inflammatory disease affecting the central nervous system, causing demyelination and axon loss. Cognitive impairment is also prevalent in patients. This study aims to measure magnetic resonance imaging (MRI) findings and their relation to cognitive impairments in MS patients.
Materials and Methods: This cross-sectional analytical study was conducted on 50 patients with a definite diagnosis of MS at Firoozgar Hospital in Tehran Province, Iran, from 2019 to 2021. MRI, complete neurological and psychological examinations, and information documented in the records were used to prepare a complete list of clinical, neurological, and psychological manifestations. The severity of these symptoms was assessed, and patients were scored according to the expanded disability status scale (EDSS), cholinergic pathways hyperintensities scale (CHIPS), and brief international cognitive assessment for multiple sclerosis (BICAMS) criteria.
Results: This study included 36 women and 14 men with a mean age of 34.14±9.4 years. Relapse and remission were observed in 70% of patients. CHIPS score had a significant relationship with spinal symptoms. Also, the BICAMS score of patients showed a significant relationship with limbic involvement in MRI. The third ventricular diameter and CHIPS score were positively correlated with the BICAMS score. Patients’ EDSS score had a significant relationship with the symbol digit modalities test (SDMT) score.
Conclusion: In this study, a significant relationship is observed between the size of the third ventricle and the CHIPS score with decreased cognitive function in MS patients. Therefore, MRI can be used to suspect cognitive disorders in MS patients. |
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| کلیدواژه‌های انگلیسی مقاله |
Multiple sclerosis, Magnetic resonance imaging, Cognition |
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| نویسندگان مقاله |
| Ramin Ebrahimi
Department of Radiology, School of Medicine, Firoozgar General Hospital, Iran University of Medical Sciences, Tehran, Iran.
| Hamideh Kateb
Department of Radiology, School of Medicine, Firoozgar General Hospital, Iran University of Medical Sciences, Tehran, Iran.
| Saeedreza Moshfeghi
Department of Ophthalmology, Eye Research Center, School of Medicine, Five Senses Health Research Institute, Hazrat-e Rasool General Hospital, Iran University of Medical Sciences, Tehran, Iran.
| Fahimeh Haji Akhoundi
Department of Neurology, School of Medicine, Firoozgar General Hospital, Iran University of Medical Sciences, Tehran, Iran.
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| نشانی اینترنتی |
http://jvessels.muq.ac.ir/browse.php?a_code=A-10-31-26&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
vascular neurological diseases |
| نوع مقاله منتشر شده |
پژوهشی |
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