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Journal of Client-Centered Nursing Care، جلد ۱۰، شماره ۴، صفحات ۷-۷
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
The Effects of Vitamin D Supplementation on the Sexual Function and Sex Hormones in Women with Multiple Sclerosis: A Randomized Controlled Clinical Trial |
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| چکیده انگلیسی مقاله |
Background: Sexual dysfunction is the most common and challenging complication among women with multiple sclerosis (MS). Despite investigations into the impact of taking vitamin D on sexual function (SF), research findings have not definitively recommended its use. This study aimed to evaluate the effects of vitamin D supplementation on SF and sex hormones among women with MS.
Methods: This triple-blind, randomized, placebo-controlled clinical trial was conducted on 62 married women with MS and vitamin D deficiency successively recruited from a specialized clinic for neurology in Tehran, Iran, between August 2017 and February 2018. The subjects were randomly allocated to either experimental or control group (n=31/each group). Subjects in the experimental and control groups received two 2000-IU vitamin D and two placebo tablets per day for 12 consecutive weeks, respectively. Serum levels of sex hormones and their SF were evaluated before and after the intervention. The SF assessment was performed using the Female Sexual Function Index (FSFI). Data were analyzed using independent-sample t-test, paired t-test, Fisher’s exact test, Mann-Whitney-U test and Chi-square in SPSS software (v. 22.0). The level of significance was determined at lower than 0.05.
Results: The findings revealed no significant difference between the two groups in terms of sex hormones, level of Vitamin D and SF before intervention. The study results indicated that taking vitamin D supplementation for 12 weeks significantly impacts the improvement of SF and sex hormones (P<0.05).
Conclusion: Twelve weeks’ consumption of vitamin D supplementation may improve sexual function and sex hormones among women with MS.
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| کلیدواژههای انگلیسی مقاله |
Multiple sclerosis, Sexual dysfunction, Vitamin D, Randomized controlled trial, Women |
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| نویسندگان مقاله |
| Simin Zarabadi-pour
Master of Midwifery Education, School of Nursing and Midwifery, Iran University of Medical Sciences
| Mohammad Eghbali
Assistant Professor of Nursing, School of Nursing and midwifery, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran
| Leila Amini
Reproductive Health, Nursing Care Research Center (NCRC), Associate Professor, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
| Seyed Massood Nabavi
Neurologist, Department of Neurology and Cognitive Science Research Institute of Cellular Sciences, Royan Research Center, Tehran, Iran
| Hamid Haghani
Department of biostatistics, Iran University of Medical Sciences, Tehran, Iran
| Homa Sadeghi Avval Shahr
Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
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| نشانی اینترنتی |
http://jccnc.iums.ac.ir/browse.php?a_code=A-10-499-2&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
پژوهشی |
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