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عنوان انگلیسی Evaluation of Apoptosis Evidence in Oral Mucosa of Patients Undergoing CT Scan
چکیده انگلیسی مقاله Computed Tomography (CT) scanning is a widely used diagnostic technique in medical imaging, particularly in the head and neck region. Although it provides high-resolution images, concerns remain about the potential cytotoxic and genotoxic effects of ionizing radiation. This study aimed to assess the impact of CT scan radiation on the epithelial cells of the oral mucosa, including the buccal, gingival, and lingual regions. Cytological samples were collected before and after CT scan exposure using a cytobrush, and cellular damage was analyzed using the Papanicolaou (Pap) staining method. The slides were assessed by a pathologist for each cellular parameter, recording abnormalities per 1000 cells. The results revealed a significant increase in nuclear abnormalities such as micronuclei, pyknosis, nuclear budding, and binucleated cells, especially in the gingival mucosa. Statistical analysis indicated significant differences between pre- and post-exposure samples (p < 0.05). This study underscores the cytotoxic and genotoxic risks associated with CT scans and highlights the need for careful consideration of radiation exposure, particularly in the head and neck region.
 
کلیدواژه‌های انگلیسی مقاله Cytotoxicity, Radiation, Tomography, X-Ray, Oral Mucosa

نویسندگان مقاله روشنک غفاری | Roshanak Ghafari
Associate professor


آزاده ترک زاده | Azade Tork Zadeh
Associate professor


آتوسا امین زاده | Atousa Aminzadeh
Associate professor


ایمانه روشن ضمیر | Imaneh Roshanzamir
Associate professor


سعید طرازی جمشیدی | Saeede Taraz Jamshidi
Associate professor



نشانی اینترنتی http://jvessels.muq.ac.ir/browse.php?a_code=A-10-184-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده interventional vascular radiology
نوع مقاله منتشر شده پژوهشی
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