| چکیده انگلیسی مقاله |
Background and Objectives In many patients with ulcerative colitis, control of the disease is possible
through pharmacological therapies, but in some cases, surgery is indicated. So far, no comprehensive
study has been published in Iran on the consequences of surgery in children with ulcerative colitis. The
present study was conducted to explore this topic.
Subjects and Methods In a 10-year period, we investigated all children with ulcerative colitis who were
admitted to Mofid Children Hospital, Tehran City, Iran, with the indication for surgery. We evaluated the
children's information on demographic characteristics, surgical indications, duration of medical treatment,
type of surgical procedure, and complications of surgery.
Results A total of 21 patients underwent surgery during these years. The mean age of the patients was
11.12±5.65 (Mean±SD) years. About 42.9% were male. In terms of surgical indications, we observed anemia
in 100% of the patients, intestinal bleeding in 33.3%, failure to thrive (FTT) in 14.3%, recurrent defecation
in 9.5%, and severe colic abdominal pain in14.3%. In terms of early surgical complications, intestinal
perforation was seen in 4.8% of the patients, peritonitis in 4.8%, wound infection in 23.8%, pelvic abscesses
in 14.3%, deep vein thrombosis in 4.8%, intestinal obstruction in 9.5%, pouchitis in 9.5% and anal fissure
in 4.8%. Also, 23.8% of patients underwent redo laparotomy to improve surgical complications. The mean
follow-up period of patients in terms of surgical outcomes was 6.79 ± 4.24 (±SD) years. During this period,
improvement in gastrointestinal function was reported in 100% of patients. Long-term surgery complications
included delayed fistulas in 23.8%-of cases and fecal incontinence in 4.8% of cases. The free survival
rates 5 and 10 years after surgery were estimated to be 92.3% and 56.4%, respectively.
Conclusion Surgical treatment in children with ulcerative colitis, who are candidates for surgery, accompanies
by favorable outcomes and correctable short- and long-term complications. |