|
|
Basic and Clinical Neuroscience، جلد ۱۶، شماره ۳، صفحات ۰-۰
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Predictors of Quality of Life in Patients with Parkinson's Disease: A Multicenter Case-Control Study |
|
| چکیده انگلیسی مقاله |
Background: Parkinson's disease (PD) is a common neurodegenerative disease whose motor and non-motor complication greatly affect a person's quality of life (QoL). This study aims to investigate the QoL of these patients using the PDQ-39 questionnaire and identify the prognostic factors associated with their QoL.
Method: In the current case-control study, the QoL of two groups (211 controls and 211 cases) was investigated and compared using the PDQ-39 questionnaire. Prognostic factors associated with QoL were determined using multivariate logistic regression analysis.
Results: A number of 422 patients with the mean age of 59.8 ± 13.7 years were included in the study. The mean score of PDQ-39 in the case group was significantly higher in all subscales except Social support compared to the control group. The mean score of PDQ-39 was significantly higher in the patients with non-DBS (53.9 ± 21.1 (than those with DBS (42.22 ± 18.1(, especially in the sub-scales of Mobility, Activities of daily living, Cognition, and Communication. As the stage of the disease increases, the mean score of PDQ-39 in these patients increases significantly. The results of multivariate analysis showed that gender, patient age, smoking, education level, duration of disease, patient stage, and intervention with DBS were significantly related to patients' QoL (P<0.05).
Conclusion: In conclusion, this study highlights the significant impact of DBS on PD patients' QoL, especially in sub-scales of mobility, daily activities, emotional well-being, and cognition. Moreover, identifying the main prognostic factors in QoL (gender, age, smoking status, educational level, disease duration, and stage) can lead to avenues for improving these patients' lives. |
|
| کلیدواژه‌های انگلیسی مقاله |
Parkinson, Quality of life, PDQ-39 questionnaire, Prognostic factors |
|
| نویسندگان مقاله |
| Aida Moarrefzadeh
Department of Psychology, Master’s Degree Student of Psychology, Ahar Branch, Islamic Azad University, Ahar, Iran.
| Sadra Sarandili
Department of Health Sciences, Curtin Medical School, Curtin University, Perth,WA, Australia.
| Nogol Motamed-Gorji
Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
| Fatemeh majdolashrafi
Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Mansour Bahardoust
Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Safa Mousavi
Department of Public Health, College of Health and Human services, Carifornia state University, Fresno, CA, USA.
| Neda Hashemi
Fellowship of Perinatology, Endometriosis Research Center, Iran University of Medical Sciences, Tehran, Iran.
| Arash Sarveazad
Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
| Mohammadhossein Vazirizadeh-Mahabadi
Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.
| Seyed Amirhassan Habibi
Movement Disorders Fellowship, Iran University of Medical Sciences, Tehran, Iran.
|
|
| نشانی اینترنتی |
http://bcn.iums.ac.ir/browse.php?a_code=A-10-6859-1&slc_lang=en&sid=1 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Cellular and molecular Neuroscience |
| نوع مقاله منتشر شده |
Original |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|