Auditory and Vestibular Research، جلد ۲۴، شماره ۴، صفحات ۱۹۳-۲۰۰

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عنوان انگلیسی Vestibular function can be affected by autoimmune processes in rheumatoid arthritis
چکیده انگلیسی مقاله Background and Aim: Autoimmune inner ear disease (AIED) may accompany certain systemic conditions, such as rheumatoid arth­ritis, and manifest audiovestibular dysfunction. This study aimed to compare the vestibular function between rheumatoid arthritis (RA) patients and normal subjects using cervical vestibular-evoked myogenic potentials and caloric tests. Methods: In this cross-sectional study, 25 patients with RA and 20 normal subjects underwent pure tone audiometry, acoustic immittance, cervical vestibular-evoked myo­genic potentials (cVEMPs), and bithermal calo­ric test which eye movements were recorded by videonystagmography. Results: Sensorineural hearing loss was found in 40% of patients with rheumatoid arthritis, which was significantly higher than controls (p< 0.05). Biphasic waveforms of cVEMPs were obtained from all of the participants. There were no significant differences in mean peak-to-peak amplitude and asymmetry ratio between the two groups (p>0.05). The mean peak latency of p13 was significantly higher in RA patients (p< 0.05). The mean peak latency of n23 was statistically different in the left ear (p< 0.05), but in the right ear the difference was not significant (p>0.05). Unilateral weakness in patients with RA were significantly higher than those in the control group (p< 0.05). The values of direc­tional preponderance were not significantly different between groups (p>0.05). Conclusion: Audiovestibular dysfunction may present in the patients with rheumatoid arthritis to a varying degree. The possible pathology was discussed in here. Further studies may shade more light to the pathogenesis of the AIED.
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نویسندگان مقاله ناهید حیدری | nahid heydari
department of audiology, school of rehabilitation, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

فهیمه حاجی ابوالحسن | fahimeh hajiabolhassan
department of audiology, school of rehabilitation, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

جمیله فتاحی | jamileh fatahi
department of audiology, school of rehabilitation, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

شفیعه موثقی | shafieh movaseghi
rheumatology research center, imam khomeini hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

شهره جلایی | shohreh jalaie
biostatistics, school of rehabilitation, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)


نشانی اینترنتی http://avr.tums.ac.ir/index.php/avr/article/view/28
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