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Caspian Journal of Neurological Sciences، جلد ۳، شماره ۱۱، صفحات ۲۰۶-۲۱۳
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The Evaluation and Comparison of Oxidative Stress in Hemorrhagic and Ischemic Stroke |
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| چکیده انگلیسی مقاله |
Background: Among different mechanisms, oxidative stress has a possible role in neural injury in cerebrovascular events. Objectives: Assessment the oxidants-antioxidants imbalance in ischemic and hemorrhagic strokes. Materials and Methods: Serum level of malondialdehyde, the main marker of lipid peroxidation, and total antioxidant capacity were measured in a group of 48 stroke patients consisting of 24 ischemic and 24 hemorrhagic cases with confirmed diagnosis by brain CT scan. Lesion volume and modified National Institutes of Health Stroke Scale (NIHSS) in ischemic stroke, as well as location and volume of hematoma in hemorrhagic stroke based on the first brain CT scan were determined as study variables. Results: These two major groups did not have different oxidative profile. Low levels of total antioxidant capacity and high levels of malondialdehyde were associated with higher lesion volume in hemorrhagic stroke patients. Conclusions: This data suggested that oxidative stress is associated with lesion volume and therefore severity of hemorrhagic stroke. |
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| کلیدواژه‌های انگلیسی مقاله |
Oxidative Stress, Malondialdehyde, Stroke |
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| نویسندگان مقاله |
علی شعیبی | ali shoeibi
department of neurology, faculty of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
نیلوفر رزمی | nilufar razmi
department of neurology, faculty of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
علی قابلی قابلی | ali ghabeli juibary
department of neurology, faculty of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
سید اسحاق هاشمی | seyed isaac hashemy
surgical oncology research center, mashhad university of medical sciences, mashhad, iran; hashemyi@mums.ac.ir
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
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| نشانی اینترنتی |
http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-87&slc_lang=en&sid=en |
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دریافت فایل مقاله |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
پژوهشی |
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