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Anatomical Sciences Journal، جلد ۱۰، شماره ۴، صفحات ۲۹-۳۳
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Lectin Histochemical Study of GalNac and GlcNac Containing Glycoconjugates in Colon Adenocarcinoma |
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| چکیده انگلیسی مقاله |
Introduction: Alteration of terminal sugars of Glycoconjugates is one of the important aspects of neoplasia. The aim of the present study was to identify GalNac and GlcNac containing glycoconjugates in different grades of neoplastic cells in adenocarcinoma of colon. Methods: Histological sections prepared from paraffin blocks belong to 30 patient of colon adenocarcinoma obtained from Khatam-Al-Anbia hospital in Zahedan, Iran and stained by H-E, PAS, WGA and SBA/Alcian blue lectins. Histologic slides were graded histochemically (0-3) according to staining intensity, and collected data were analyzed by SPSS software. Results: Statistical analysis showed only a significant difference in staining intensity for SBA lectin P< 0.001) . Furthermore with increasing the histopathological grades, the frequency of positivity of neoplastic cells for GalNac and GluNac was also increased. Conclusion: The pattern of staining of neoplastic cells to WGA and SBA lectins were changed with increasing of histopathological grades. |
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| کلیدواژه‌های انگلیسی مقاله |
Colon, Adenocarcinoma, Glycoconjugates, GalNac, GlcNac. |
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| نویسندگان مقاله |
محمدرضا عرب | mohamad reza arab
professor of histology, department of anatomical sciences, school of medicine, cell and molecular research center, zahedan university of medical sciences, zahedan, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)
علیرضا رجحان | ali reza rojhan
m sc in anatomical sciences, school of medicine, zahedan university of medical sciences, zahedan, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)
مهدی جهانتیغ | mehdi jahantigh
assistant professor of pathology, department of pathology, school of medicine, cell and molecular research center, zahedan university of medical sciences, zahedan, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)
مهدی محمدی | mehdi mohammadi
assistant professor of biostatistics, department of biostatistics, school of medicine, health promotion center, zahedan university of medical sciences, zahedan, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)
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| نشانی اینترنتی |
http://www.anatomyjournal.ir/browse.php?a_code=A-10-25-28&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Macro - Anatomy |
| نوع مقاله منتشر شده |
Original |
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