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Iranian Journal of Health Sciences، جلد ۶، شماره ۳، صفحات ۰-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Effects of Solvents on the In-vitro Antioxidant Activity of Dennettia tripetala G. Baker and Milicia excelsa (Welw.) C. Berg Root Extracts |
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| چکیده انگلیسی مقاله |
Background and Purpose: The root extracts of Dennettia tripetala G. Baker and Milicia excelsa (Welw.) C. Berg was investigated for their in-vitro antioxidant activities. Materials and Methods: The pulverized roots of Dennettia tripetala and Milicia excelsa were extracted separately by cold maceration using ethyl acetate, methanol, n-butanol and water respectively as the extracting solvents. In-vitro antioxidant, the activity of root extracts was then investigated using DPPH model. The results obtained was analyzed using One-way Analysis of Variance (ANOVA) involving GraphPad Prism 5 Software. Results: The antioxidant assay of various extracts, using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging model, revealed that the ethanol and n-butanol extracts of D. tripetala had better radical scavenging activity with IC50 values of 2.02 and 0.631 µg/mL for ethanol and n-butanol extracts, respectively. The methanol and ethanol extracts of M. excelsa showed higher radical scavenging capacity with IC50 of 0.194 and 8.84 µg/mL compared to that of the ascorbic acid which had IC50 value of 4.60 µg/mL. Conclusion: The radical scavenging ability of the extracts could be attributed to the presence of flavonoids and phenolics. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
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| نشانی اینترنتی |
http://jhs.mazums.ac.ir/browse.php?a_code=A-10-658-4&slc_lang=fa&sid=1 |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
بهداشت |
| نوع مقاله منتشر شده |
پژوهشی |
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