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Basic and Clinical Neuroscience، جلد ۳، شماره ۴، صفحات ۶۰-۶۷
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Effects of Infantile Repeated Hyperglycemia on Behavioral Alterations in Adult Rats |
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| چکیده انگلیسی مقاله |
Anxiety symptoms have been reported to be present in many patients with diabetes mellitus. However, little is known about the effects of hyperglycemia in critical periods of the central nervous system development. We assessed locomotive, exploratory, and anxiety behaviors in adult rats that remained from infantile repeated hyperglycemia by the open field and elevated plus maze tests. Our findings showed significant hypo activity, reduced locomotive/exploratory activities, increased fear related behaviors, and anxiety state between hyperglycemic and control adult males and the same differences were observed among females. In addition, no significant behavioral alterations between male and female animals were observed. This study determined that repeated increments in daily blood sugar levels in newborns may affect neuronal functions and provide behavioral abnormalities in adults. |
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| کلیدواژههای انگلیسی مقاله |
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| نویسندگان مقاله |
ملیحه مقدمی | malihe moghadami
علی مقیمی | ali moghimi
عماد آهنگر | emad ahangar
راضیه جلال | razieh jalal
مرتضی بهنام رسولی | morteza behnam rassouli
ناصر مهدوی شهری | naser mahdavi shahri
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| نشانی اینترنتی |
http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-122&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Cellular and molecular Neuroscience |
| نوع مقاله منتشر شده |
Original |
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