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Basic and Clinical Neuroscience، جلد ۲، شماره ۴، صفحات ۵-۱۱
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The Power of Classic Music to Reduce Anxiety in Rats Treated with Simvastatin |
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| چکیده انگلیسی مقاله |
Introduction: This study was designed to investigate the effects of music in Wistar rats after sub-chronic treatment of simvastatin. The rats were orally administered with either simvastatin or saline (controls). After 4 weeks of drug treatment, the rats were selected for behavioral studies. The rats were exposed to music 24 hours before behavioral tests (Mozart’s piano sonata, KV361, Largo). Results: The experiments suggest that exposure to chronic treatment with simvastatin (1 or 10 mg/kg/day) reduced anxiety levels in rats when associated with Mozart music in an elevated plus-maze. Discussion: These results indicate that music can serve as an effective adjuvant in rats treated with simvastatin, and that this species could potentially be used in other preclinical models utilizing musical interventions. Methods: |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
júlia niehues da cruz | júlia niehues da cruz
universidade do extremo sul catarinense, santa catarina, brazil
دانیلا delwing de لیما | daniela delwing de lima
universidade da região de joinville, santa catarina, brazil
débora delwing دال magro | débora delwing dal magro
universidade regional de blumenau, santa catarina, brazil
جوز geraldo pereira da cruz | josé geraldo pereira da cruz
department of natural sciences, universidade regional de blumenau, santa catarina, brazil
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| نشانی اینترنتی |
http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-70&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Clinical Neuroscience |
| نوع مقاله منتشر شده |
Original |
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