Basic and Clinical Neuroscience، جلد ۱، شماره ۳، صفحات ۴۴-۴۹

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عنوان انگلیسی Effects of Methadone Maintenance Treatment on Decision-Making Processes in Heroin-Abusers: A Cognitive Modeling Analysis
چکیده انگلیسی مقاله A B S T R A C TIntroduction: Although decision-making processes have become a principal target of study among addiction researchers, few researches are published according to effects of different treatment methods on the cognitive processes underlying decision making up to now. Utilizing cognitive modeling method, in this paper we examine the effects of Methadone maintenance treatment (MMT) on cognitive processes underlying decision-making disorders in heroin-abusers. Methods: For this purpose, for the first time, we use the balloon analog risk task (BART) to assess the decision-making ability of heroin-abusers before and after treatment and compare it to the non heroin-dependent subjects. Results: Results demonstrate that heroin-abusers show more risky behavior than other groups. But, there is no difference between the performance of heroin-abusers after 6 months of MMT and control group. Modeling subjects’ behavior in BART reveals that poor performance in heroin-abusers is due to reward-dependency and insensitivity to evaluation. Discussion: Results show that 6 months of MMT decreases reward-dependency and increases sensitivity to evaluation.
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نویسندگان مقاله آرش خدادادی | arash khodadadi
e-mail address akhodadadi@ee.iust.ac.ir. tel. 98 9133264404


امیر دزفولی | amir dezfouli
center of excellence for control amp;amp; intelligent processing department of electrical amp;amp; computer engineering, neuro cognitive laboratory, iranian national center for addiction studies,


پگاه فخاری | pegah fakhari
center of excellence for control amp;amp; intelligent processing department of electrical amp;amp; computer engineering,


حامد اختیاری | hamed ekhtiari
neuro cognitive laboratory, iranian national center for addiction studies,



نشانی اینترنتی http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-32&slc_lang=en&sid=en
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Cellular and molecular Neuroscience
نوع مقاله منتشر شده Original
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