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، جلد ۱۱، شماره ۴، صفحات ۱۹-۲۶
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Mercury Intoxication in Rats: Iron and Vitamin B6 as A Potential Therapy |
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| چکیده انگلیسی مقاله |
Background: Mercury in any form is poisonous and mercury toxicity most commonly affects the nervous, gastrointestinal (GI) and urinary systems. The aim of this study was to investigate the specific effect associated with mercury toxicity and to evaluate the effectiveness of iron and vitamin B6 supplement on mercury-induced toxicities in rats. Methods: This experiment was performed on 25 rats. All rats were randomly divided into five equal groups (5×5). Toxic signs and body weight change, hematological parameters like total erythrocyte count (TEC), total leukocyte count (TLC), hemoglobin content (Hb%) and packed cell volume (PCV) and postmortem changes in rats were investigated. Results: Rats treated with mercury intoxication showed severe toxic signs and significantly (P< 0.01) reduced TEC, TLC, Hb content and PCV. However, rats treated with mercury intoxication in combination with iron and vitamin B6 showed physiological levels of hematological parameters. Mercury intoxication induced the congestion and necrosis in lung, liver, heart and kidney, whereas combined use of mercury intoxication, iron and vitamin B6 recovered the condition. Conclusion: Combined use of iron and vitamin B6 is highly protective against mercury toxicity. |
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| کلیدواژههای انگلیسی مقاله |
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| نویسندگان مقاله |
| Mohammad Taimur Islam
Department of Pathobiology, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh.
| Anup Kumar Talukder
Department of Gynecology, Obstetrics and Reproductive Health, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh.
| Milton Talukder
Department of Physiology and Pharmacology, Patuakhali Science and Technology University, Babugonj, Barisal, Bangladesh.
| Mohammad Rohul Amin
Department of Physiology and Pharmacology, Patuakhali Science and Technology University, Babugonj, Barisal, Bangladesh.
| Khondoker Jahengir Alam
Department of Pathology and Parasitology, Patuakhali Science and Technology University, Babugonj, Barisal, Bangladesh.
| Mohammad Golam Haider
Department of Pathobiology, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh.
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| نشانی اینترنتی |
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-429-1&slc_lang=en&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2737/article-2737-2049581.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
عمومی |
| نوع مقاله منتشر شده |
پژوهشی |
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