، جلد ۸، شماره ۲۴، صفحات ۱۰۰۴-۱۰۱۰

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عنوان انگلیسی Heavy Metals (Lead and Cadmium) in some Medicinal Herbal Products in Iranian Market
چکیده انگلیسی مقاله Background:The use of herbal or medicinal plants in various forms has been popular for thousands of years. It is estimated that about 70–80% of the world’s population relies on alternative medicine, mainly of herbal origin. However, due to the nature and sources of these plants, they are sometimes contaminated with toxic heavy metals, which pose serious health risks to consumers. Herbal formulations, especially those used in the treatment of diseases such as hypertension, diabetes, and weight loss may require long-term usage and the patient might be at risk of heavy metal poisoning. In this study, the levels of toxic heavy metals (Pb, Cd) were evaluated in 11 Iranian common herbal drugs for their health implications. Methods: In this investigation, concentrations of lead and cadmium were quantitatively determined in Iranian herbal drugs sampled from pharmacies in Tehran, Iran, using atomic absorption spectrophotometry (wet digestion). Results: The results indicated that lead and cadmium were present in all investigated herbal drugs. The concentrations of metals in drugs ranged from 0.19 to 1.75 µg/g for Cd and 9.61 to 52.74 µg/g for Pb. Conclusion:The concentrations of lead and cadmium were higher than the maximum permissible daily levels in the majority of these herbal drugs, whereas the quantities of Pb and Cd were well below provisional tolerable weekly intake (PTWI). Daily total intake of these metals is considered in accord with the recommended daily intake of their corresponding formulations.
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نویسندگان مقاله زهرا موسوی | Zahra Mousavi
Department of Pharmacology and Toxicology, Pharmaceutical Sciences Branch (IAUPS),Islamic Azad University, Tehran, Iran.


پریسا زیارتی | Parisa Ziarati
Department of Medicinal Chemistry, Pharmaceutical Sciences Branch (IAUPS), Islamic Azad University, Tehran, Iran


مهدیه اسماعیلی دهقی | Mahdieh Esmaeli Dehaghi
Department of Pharmacology and Toxicology, Pharmaceutical Sciences Branch (IAUPS),Islamic Azad University, Tehran, Iran.


مهناز قمی | Mahnaz Qomi
Department of Medicinal Chemistry, Pharmaceutical Sciences Branch (IAUPS), Islamic Azad University, Tehran, Iran



نشانی اینترنتی http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-2-151&slc_lang=en&sid=1
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/2737/article-2737-2049722.pdf
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده تخصصی
نوع مقاله منتشر شده پژوهشی
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