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، جلد ۷، شماره ۲۳، صفحات ۹۵۲-۹۵۵
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Electrocardiographic Manifestations of Benzodiazepine Toxicity |
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| چکیده انگلیسی مقاله |
Background: The aim of this study was to evaluate and compare the clinical and electrocardiographic (ECG) manifestations of benzodiazepines (BZs). Methods: In this retrospective study, all BZ-poisoned patients hospitalized at Loghman Hakim Hospital between September 2010 and March 2011 were evaluated. Patients’ information including age, sex, time elapsed between the ingestion and presentation, and type of the BZ used were extracted from the patients' charts and recorded. ECGs on presentation to the emergency department (ED) were evaluated and parameters such as PR interval, QRS duration, corrected QT, amplitude of S wave in lead I, height of R wave and R/S ratio in the lead aVR were also measured and recorded. Results: Oxazepam, chlordiazepoxide, lorazepam, alprazolam, diazepam, and clonazepam were ingested by 9 (3%), 13 (4.4%), 29 (9.9%), 105 (35.8%), 65 (22.2%), and 72 (24.6%) patients, respectively. Mean PR interval was reported to be 0.16 ± 0.03 sec and PR interval of greater than 200 msec was detected in 12 (4.5%) patients. Mean QRS duration was 0.07 ± 0.01sec and QRS≥120 msec was observed in 7 (2.6%) cases. Conclusion: Diazepam is the only BZ that does not cause QRS widening and oxazepam is the only one not causing PR prolongation. It can be concluded that if a patient refers with a decreased level of consciousness and accompanying signs of BZ toxicity, QRS widening in ECG rules out diazepam, whereas PR prolongation rules out oxazepam toxicity. |
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| کلیدواژههای انگلیسی مقاله |
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| نویسندگان مقاله |
ناهید کاظم زاده | Nahid Kazemzadeh
Department of Forensic Medicine and Toxicology, Iran University of Medical Sciences, Tehran, Iran.
سعید محمدی | Saeed Mohammadi
Department of Forensic Medicine and Toxicology, Iran University of Medical Sciences, Tehran, Iran.
محمدعلی امام هادی | Mohammadali Emamhadi
Department of Forensic Medicine and Toxicology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
عبداله امیرفرهنگی | Abdollah Amirfarhangi
Department of Cardiology, Hazrat Rasoul Akram(p)Hospital, Iran University of Medical Sciences, Tehran, Iran.
حسین صناعی زاده | Hossein Sanaei-Zadeh
Emergency Department /Division of Medical Toxicology, Hazrat Ali-Asghar (p) Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
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| نشانی اینترنتی |
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-2-136&slc_lang=en&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2737/article-2737-2049731.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
پژوهشی |
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