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، جلد ۴، شماره ۲، صفحات ۳۰-۳۵
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Correlations Between Plasma Sphingosine-1-phosphate (S1P) and Gene Expression of S1P Receptors with Mogenic Regulatory Factors Following Resistance Training |
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| چکیده انگلیسی مقاله |
Background: The purpose of present study was to investigate whether Sphingosine 1-phosphate (S1P) levels and its receptors gene expressions are correlated with MyoD and myogenin following resistance training. Materials and Methods: 24 eight-week-old male Wistar rats (190-250 gr) were assigned randomly to a control (N = 12) or training (N = 12) group. Rats climbed a resistance training ladder with weights attached to their tails. The content of plasma S1P and relative mRNA expression were determined by high performance liquid chromatography (HPLC) and Real-time PCR, respectively. Results: Resistance training increased the content of S1P in plasma (P = 0.001) and changed the gene expression of S1P1, S1P2 and S1P3 receptors. There were significant correlations between plasma S1P and gene expression of S1P2,3 receptors with gene expression of MyoD. There are correlations between satellite cells activation markers (MyoD and myogenin) and plasma S1P content and its receptors before and after resistance training. Conclusion: It might be concluded that S1P as a growth mediator may play an important role in skeletal muscle adaptations. |
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| کلیدواژه‌های انگلیسی مقاله |
MyoD, myogenin, S1P, S1P receptor, skeletal muscle |
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| نویسندگان مقاله |
| Ebrahim Banitalebi
Assistant professor in exercise physiology, University of Shahrekord. Shahrekord. Iran
| Reza Gharakhanlou
2- Associate professor in Exercise Physiology, Department of Sport Sciences, Tarbiat Modares University, Tehran, Iran.
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| نشانی اینترنتی |
http://rmm.mazums.ac.ir/browse.php?a_code=A-10-810-1&slc_lang=en&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/2735/article-2735-2201216.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
بیولوژی |
| نوع مقاله منتشر شده |
پژوهشی |
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