، جلد ۱، شماره ۳، صفحات ۳۴-۳۷
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عنوان انگلیسی The effect of the duration of orthognathic surgery on plasma concentration of Interleukin 6
چکیده انگلیسی مقاله Background: The cytokines have a major role in the inflammatory response to surgery and trauma. They have local effects of mediating and maintaining the inflammatory response to tissue injury, and also initiate some of the systemic changes which occur. IL-6 is one of the above mentioned cytokines, but it is not clear whether the duration of trauma or surgery has some effect on IL-6 level, so the aim of this study was to investigate the relationship between plasma levels IL-6 and duration of orthognathic surgery. Materials and Methods: Twenty eight patients underwent orthognathic surgery were enrolled in this study. Blood samples were collected one day before and 4 hours after surgery for assessment the levels of plasma IL-6 which was measured by enzyme-linked immunosorbent essay. Results: We found a significant elevation of plasma IL-6 level at 4 hours after surgery (P< 0.05). Moreover, the elevation of plasma IL-6 level was correlated with the duration of surgery. Conclusion: IL-6 is an important inflammatory mediator that its concentration is increased with the duration of surgery.
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نویسندگان مقاله | Mandana Sattari
Department of Immunology, Medical School, Shahid Beheshti University of Medical Sciences, Tehran. Iran


| Ali Peymani Mojaver
Department of Maxillo-facial Surgery, Dental School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran


| Hossein Behnia
Department of Maxillo-facial Surgery, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Golnaz Kavand
Departments of Preventive and Community Dentistry, University of Iowa, College of Dentistry, Iowa, USA


| Hassan Darbandi-Tamijani
Department of Immunology, Medical School, Shahid Beheshti University of Medical Sciences, Tehran. Iran
نشانی اینترنتی http://rmm.mazums.ac.ir/browse.php?a_code=A-10-611-1&slc_lang=en&sid=1
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/2735/article-2735-2201292.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده جراحی دهان وفک وصورت
نوع مقاله منتشر شده پژوهشی
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