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Anatomical Sciences Journal، جلد ۹، شماره ۳۷، صفحات ۰-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Effect of Neurotrophin-3 on Differentiation of Rat Hair Follicle Stem Cells into Neural Like Cells |
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| چکیده انگلیسی مقاله |
Purpose: The aim of this study was to evaluate the effect of NT-3 on the decrease of the differentiation time of bulge stem cells of rat hair follicle from neuron like cells.Materials and Methods: The bulge region of the rat whisker was isolated from and cultured in DMEM/F12 supplemented with epidermal growth factor (EGF) in 3 groups for 7, 8 and 9 days .Then 10 ng/ml NT-3 was added to each group for 3 days. Finally, cell differentiation was assessed by immunocytochemistry using βⅢ-tubulin antibody and the result was compared with control groups.Results: According to our results hair follicle bulge stem cells expressed CD34 and Nestin in 7-9 and 10-12 first days after cultivation respectively. By using NT-3 duration differentiation process the cells showed positive reaction to βⅢ-tubulin antibody.Conclusion: The results indicate that NT-3 can affect on differentiation speed even in less than 10 days |
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| کلیدواژههای انگلیسی مقاله |
Bulge of Hair Follicle, Cd34, Nestin, Nt-3, ΒⅢ-Tubulin |
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| نویسندگان مقاله |
| Fatemeh Moghani Ghoroghi
| Maliheh Nobakht
| Banfsheh Esmaeilzade
| Mehrdad Bakhtiyari
| Leila Beygom Hejazian
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| نشانی اینترنتی |
http://anatomyjournal.ir/browse.php?a_code=A-10-304-238&slc_lang=fa&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/13/article-13-2473880.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
Morphometry |
| نوع مقاله منتشر شده |
Original |
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