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Anatomical Sciences Journal، جلد ۹، شماره ۳۶، صفحات ۰-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Comparison of the effect of Growth Factors on the Development of Pre-implantation Embryos of Vitrified Mouse |
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| چکیده انگلیسی مقاله |
Purpose: To improve the development of frozen mouse embryos by adding fibroblast growth factors (FGF) and hepatocytes (HGF) to the culture medium. Materials and Methods: Two-cell mouse embryos obtained from the fallopian tube and frozen by cryotopic method were treated in T6 medium with a dose of 20 ng / ml FGF and 20 ng / ml HGF. The results of their culture were compared with control groups and the rate of embryonic development was evaluated.Results: The results showed that the rate of cleavage and development of vitrified and non-vitrified mouse embryos in the culture medium by adding growth factors was significantly increased compared to the control group (p < 0.01). There was also a significant difference in the rate of morula development between vitrified and non-vitrified embryos treated with growth factors (p < 0.05), but this difference was not observed in the rate of blastocyst formation (p> 0.05). Conclusion: The results of this study show that the addition of growth factors in the culture medium improves the pre-implantation development of mouse embryos after vitrification. |
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| کلیدواژه‌های انگلیسی مقاله |
Growth Factors, Pre-implantation Development, Vitrification |
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| نویسندگان مقاله |
| Fatemeh Ghasemian
| Mahnaz Azarnia
| Masoumeh Faghani Langroudi
| Mohammad Hadi Bahadori
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| نشانی اینترنتی |
http://anatomyjournal.ir/browse.php?a_code=A-10-304-237&slc_lang=fa&sid=1 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/13/article-13-2473884.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
Morphometry |
| نوع مقاله منتشر شده |
Original |
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