چکیده انگلیسی مقاله |
BACKGROUND: Lumpy skin disease (LSD) is a significant viral disease of cattle sometimes found in Iran. OBJECTIVES: The aim of this study was the molecular detection of LSD virus (LSDV) and the determination of their relationship with other Iranian isolates. Moreover, the origin and spread of these viruses were evaluated. METHODS: The lymph node samples taken from clinically affected cattle from the Kurdistan province of Iran were tested for LSDV using the polymerase chain reaction (PCR). RESULTS: The partial P32 gene of LSDV was detected by PCR, sequenced, and phylogenetically analyzed. The LSDVs detected in the present study were 42.98%-100% similar to other LSDVs of Iran. CONCLUSIONS: Iranian LSDV isolates in this research had the highest similarity to the isolates found in the Indian regions. However, they showed the lowest nucleotide identity with the countries located in the west and southwest of Iran, namely Turkey and Saudi Arabia LSDVs. It could be concluded that these viruses have entered Iran from the eastern borders. It seems that the monitoring of the country borders should be taken into consideration. Further studies should be carried out on LSDV pathogenesis and molecular epidemiology. |
نویسندگان مقاله |
Arash Ghalyanchilangeroudi | Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Zahra Ziafati Kafi | Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Ali Rajeoni | Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Jamil Ataii | Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Naser Sadri | Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Niusha Hajizamani | Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Leila Aghaeean | Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Sanaz Majidi | Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Hafez Sadeghi | Department of Theriogenology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Mohammadreza Ghorani | Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
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