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، جلد ۹، شماره ۱، صفحات ۲۱-۲۸
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Comparing the Effect of Grape Fermentative Product and Fresh Red Grape Juice on Antioxidant Biomarkers of Liver Mitochondria Isolated From Rats in Vitro |
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| چکیده انگلیسی مقاله |
Background: Mitochondria are a source of reactive oxygen species (ROS), and several natural compounds are used as antioxidant agents. This study aimed to investigate and compare the effects of fresh grape juice red wine on oxidative stress biomarkers in rat liver mitochondria. Materials and Methods: In this regard, mitochondria were isolated from the liver of 27 male Wistar rats (220-250 g). The isolated mitochondria were cultured in different doses of red wine and fresh red grape juice for 24, 48, and 72 h. After treatment, total antioxidant capacity, lipid peroxidation, total thiol groups, and catalase activity were determined in the isolated mitochondria of the rat liver. Results: The results confirmed the oxidant/antioxidant effects of red wine and fresh red grape juice at different times. Conclusion: According to the results, the fresh red grape juice showed higher antioxidant properties than red wine in the liver mitochondrial samples. |
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| کلیدواژه‌های انگلیسی مقاله |
Antioxidant, Grape juice, Liver mitochondria, Red wine |
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| نویسندگان مقاله |
| Amir Keshavarzi
Research Center for Behavioral Disorders and Substances Abuse, Hamadan University of MedicalSciences, Hamadan, Iran.
| Akram Ranjbar
Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
| Nejat Kheiripour
Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.
| Ali Ghaleiha
Research Center for Behavioral Disorders and Substances Abuse, Hamadan University of MedicalSciences, Hamadan, Iran.
| Alireza Soltaniyan
Department of Epidemiology, Faculty of Health, Hamadan University of Medical Sciences, Hamadan, Iran.
| Seyyed Mostafa Hashemi
Research Center for Behavioral Disorders and Substances Abuse, Hamadan University of MedicalSciences, Hamadan, Iran.
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| نشانی اینترنتی |
http://rmm.mazums.ac.ir/browse.php?a_code=A-10-760-3&slc_lang=en&sid=1 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
سم شناسی |
| نوع مقاله منتشر شده |
پژوهشی |
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