| چکیده انگلیسی مقاله |
The true prevalence of cardiac anomalies in diagnosed cases of echogenic foci remains ascertain as various studies have been carried out across various populations and with different methodologies. The primary objective of this study was to determine the precise true prevalence of cardiac anomalies found in cases with intracardiac echogenic foci. The authors individually conducted search of the electronic databases manually (Cochrane library, PubMed, EMBASE, Scopus, Web of Science). Data extraction and quality control was independently done by two reviewers and a third reviewer was involved if any conflict was to be resolved. The data was analysed by Comprehensive Meta-Analysis Software Version 2. Risk of bias assessment and strobe checklist were used for quality assessment. Out of the total 531 articles identified, 32 studies met the inclusion criteria and were included in the meta-analysis with a total sample size of 7568. The pooled prevalence of cardiac anomalies in foetus with intracardiac echogenic foci was 4.8% (95% CI 3.6-6.4). Subgroup analysis was done according to geographical distribution of cases, maternal age, gestational age, year of publication, risk of bias and ultrasonography operator. The current study represents the first and only meta-analysis concerning the prevalence of cardiac anomaly in the foetus diagnosed with ICEF. This study reiterates that a definitive relation exists between ICEF and underlying congenital heart disease. We recommend for increased training of individuals performing these ultrasonography so as to improve early detection which will ultimately enhance the care given to infant immediately post-birth. Trial registration number: PROSPERO # CRD42021253664 |
| نویسندگان مقاله |
| Amar Taksande
Department of Paediatrics, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences, SawangiMeghe, Wardha, Maharashtra State, India.
| Patel Zeeshan Jameel
Department of Paediatrics, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences, SawangiMeghe, Wardha, Maharashtra State, India.
| Rupesh Rao
Department of Paediatrics, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences, SawangiMeghe, Wardha, Maharashtra State, India.
| Bharati Taksande
Department of Medicine, Mahatma Gandhi Institute of Medical Sciences (MGIMS), Sewagram, Wardha, Maharashtra State, India.
| Sachin Damke
Department of Paediatrics, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences, SawangiMeghe, Wardha, Maharashtra State, India.
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