Journal of Pediatrics Review، جلد ۱۱، شماره ۳، صفحات ۳-۳

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عنوان انگلیسی The Effect of Chicory on Bilirubin Level in Newborns Suffering from Jaundice: A Systematic Review
چکیده انگلیسی مقاله Background: Jaundice is the most prevalent reason for hospitalization among infants during their first month of birth, and herbal medicine has long been used alongside phototherapy to treat this disease. Objectives: The present systematic review thus seeks to investigate the influence of chicory on bilirubin levels in infants with jaundice. Methods: In this systematic review study, Iranian databases including Barekat Gostar, Scientific Information Database (SID), Iran Doc, Magiran, and international databases including Cochrane Library, Web of Science, Scopus, PubMed, and Google Scholar search engines were explored with standard keywords to retrieve relevant studies. Results: Among the seven included articles with a sample size of 408 (204 people in the intervention group and 204 in the control group) and execution date of 2006-2020, four studies were in vitro and three were randomized clinical trials (RCTs). Among these studies, mothers' pregnancy duration ranged between 30.9 and 38.8 weeks, infants' age ranged between three and seven days, and their weight ranged between 1,544 and 3,316gram. Although chicory administration varied across the studies, four studies reported it to be effective in reducing infants' bilirubin, whereas the other three articles reported that chicory left no impact on bilirubin levels in infants. Conclusions: Iran was the only country that had evaluated the effect of chicory on neonatal jaundice in the form of several research studies, but due to the limited number of studies and the different dosage of chicory, the way of consuming chicory, the type of studies, the age and weight of babies, we could not make a general and accurate Comment on the efficacy of chicory.    
کلیدواژه‌های انگلیسی مقاله Chicory, Bilirubin, Jaundice, Infant, Systematic review

نویسندگان مقاله | Moloud Fakhri
Traditional and Complementary Medicine Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.


| Amirsaeed Hosseini
Complementary and Alternative Medicine Research Center, Mazandaran University of Medical Sciences, Sari, Iran.


| Roya Farhadi
Pediatric Infectious Diseases Research Center, Mazandaran University of Medical Sciences, Sari, Iran.


| Mahmood Moosazadeh
Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.


| Mohammad Azadbakht
Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.


| Vahidreza Berneti
Medical Student at Medical School, Mazandaran University of Medical Sciences, Sari, Iran.



نشانی اینترنتی http://jpr.mazums.ac.ir/browse.php?a_code=A-10-1047-3&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Neonatology
نوع مقاله منتشر شده Systematic Review
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