Immunoregulation، جلد ۳، شماره ۱، صفحات ۲۹-۳۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Interleukin-6 as a Potential Predictor of COVID-19 Disease Severity in Hospitalized Patients and its Association with Clinical Laboratory Routine Tests
چکیده انگلیسی مقاله Background: Researchers have already reported a high level of interleukin (IL)-6 in patients affected by Coronavirus Disease 2019 (COVID-19). In this study, we investigated the surge of IL-6 level and its association with the clinical and paraclinical markers in these patients.
Materials and Methods: The study sample comprised 205 confirmed hospitalized patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and 70 healthy volunteer individuals. Routine laboratory examinations, including hematology, biochemistry, and hormone analysis, as well as IL-6 level measurement, were conducted. The patients grouped into 5 based on their IL-6 levels. Then, they were compared with regard to their need for mechanical ventilator and clinical laboratory routine tests.
Results: IL-6 levels were significantly higher in hospitalized patients compared with healthy individuals (P<0.001). The IL-6 level was approximately 10-fold of the normal range in 22.9% of the patients. Also, more than 56.1% of them signify IL-6 over 3-fold of the normal range. IL-6
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله Abdolrahman Rostamian |
Department of Rheumatology, Valiasr Hospital, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Tooba Ghazanfari |
Immunoregulation Research Center, Shahed University, Tehran, Iran.

Jalil Arabkheradmand |
Defense Health Research Center, Tehran, Iran.

Maryam Edalatifard |
Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Sara Ghaffarpour |
Immunoregulation Research Center, Shahed University, Tehran, Iran.

Mohammad Reza Salehi |
Department of Infectious Diseases, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Seyed Reza Raeeskarami |
Department of Pediatrics, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Maedeh Mahmoodi Aliabadi |
Central laboratory, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Maryam Rajabnia Chenary |
Defense Health Research Center, Tehran, Iran.

Ensie Sadat Mirsharif |
Immunoregulation Research Center, Shahed University, Tehran, Iran.

Davoud Jamali |
Department of Immunology, Shahed University, Tehran, Iran.

Mohammad Reza Sattarian |
Simorgh Clinical Laboratory, Tehran, Iran.

Reza Najafizadeh |
Department of Rheumatology, Valiasr Hospital, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Sajjad Hosseinieselki Sari |
Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Samira Jafarpour |
Defense Health Research Center, Tehran, Iran.

Elham Nezhadseifi |
Department of Rheumatology, Valiasr Hospital, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Shafieh Movasseghi |
Department of Rheumatology, Valiasr Hospital, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Elahe Baharvand |
Department of Internal Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Saba Beiranvand |
Department of nursing, Islamic Azad University, Tehran, Iran.

Azin Roomi |
Department of nursing, Islamic Azad University, Tehran, Iran.

Mohammad Mehdi Naghizadeh |
Non-communicable Diseases Research Center, Fasa University of Medical Science, Fasa, Iran.

نشانی اینترنتی https://immunoreg.shahed.ac.ir/article_1226_ea8cbc4695a77e3ae46a35922ade603b.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات